Results 201 to 210 of about 502,158 (254)

A Unified Framework for Statistical Inference and Power Analysis of Single and Comparative $$ {F}_{\beta } $$ Scores. [PDF]

Stat Med
Hsu CY, Liu Q, Shyr Y.
europepmc   +1 more source

ProSiteHunter: A Unified Framework for Sequence‐Based Prediction of Protein‐Nucleic Acid and Protein‐Protein Binding Sites

Advanced Science, EarlyView.
This study proposed a unified sequence‐based framework for protein binding site prediction, which adopted a tri‐track semantic multi‐source feature fusion strategy to effectively capture diverse macromolecular interaction sites and further improved the accuracy of antibody‐antigen interaction prediction.
Dongliang Hou, Qihang Zhen, Zexin Lv, Xinyue Cui, Suhui Wang, Minghua Hou, Zhan Zhou, Xiaogen Zhou, Guijun Zhang   +8 more
wiley   +1 more source

Establishment of duplex multi-enzyme isothermal rapid amplification detection method for bovine astrovirus and norovirus. [PDF]

Front Vet Sci
Jiang L, Zhao Y, Zhang Q, Luo W, Zhou J, Yu B.   +5 more
europepmc   +1 more source

Pressure‐Induced Drift Artifacts in Stretchable Liquid Metal ThinFilm Electrocardiogram Electrodes

Advanced Science, EarlyView.
A stretchable LM electrode integrated with a strain sensor enables in situ quantitative investigation of drift artifact and skin deformation. This reveals the significance of pressure‐induced drift artifact and its intimate relationship with the skin potential model.
Ding Li, Zi‐Gan Xu, Zhi‐Kang Chen, Shuo‐Yan Xu, Jia‐Yi Cui, Si‐Yuan Wo, Zi‐Xu Wang, Yi‐Kun Liu, Jia‐Ju Yin, Hou‐Fang Liu, Xiao‐Ming Wu, Lu‐Qi Tao, Yi Yang, Tian‐Ling Ren   +13 more
wiley   +1 more source

Fault-tolerant pedigree reconstruction from pairwise kinship relations. [PDF]

Bioinformatics
Huang EC, Li KA, Narasimhan VM.
europepmc   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Fluorinated Amphiphilic Dendrimer to Improve PET Imaging of Cancer. [PDF]

Small
Louis B, Roussel T, Cruz-Dubois T, Ding L, Lyu Z, Laurini E, Ou J, Balasse L, Chabert A, Nail V, Bouhlel A, Dignat-George F, Gattacceca F, Pricl S, Guillet B, Peng L, Garrigue P.   +16 more
europepmc   +1 more source

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

Advanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt   +15 more
wiley   +1 more source

CREAT: A CRISPR‐Based Genome Trimming Strategy for Systematic Identification of Dispensable Regions and Rapid Genome Reduction

Advanced Science, EarlyView.
Current genome‐reduction methods work in a trial‐and‐error fashion, constituting a long‐standing bottleneck in the research. We developed CREAT (CRISPR‐based genome trimming with a multi‐homology‐arm template), a CRISPR‐based genetic approach that enables systematically classifying essential versus non‐essential genomic regions and subsequently ...
Guanhua Yuan, Zhe Gao, Yingxuan Qi, Yang Zhang, Xuhui Tian, Pengpeng Zhao, Xu Feng, Qunxin She   +7 more
wiley   +1 more source