CauFinder: Steering Cell‐State and Phenotype Transitions by Causal Disentanglement Learning
CauFinder combines causal disentanglement modeling and network control to prioritize causal drivers of cell‐state transitions from observational transcriptomic data. The framework separates transition‐relevant signals from spurious associations, nominates intervention targets across biological and disease contexts, and identifies DAAM1 as an actionable
Chengming Zhang +11 more
wiley +1 more source
Quantitative susceptibility mapping demonstrates ageing-related long-term structural brain changes in adult rats after mild ischaemic stroke. [PDF]
Tao Z +8 more
europepmc +1 more source
Super‐Resolution and High‐Data‐Density Acoustic Meta‐Hologram via Amplitude and Phase Coupling
A super‐resolution acoustic meta‐hologram utilizes amplitude‐phase coupling under energy conservation constraints to overcome the traditional diffraction limit. This conceptually advanced approach achieves high‐fidelity acoustic field reconstruction and dense information transmission, unlocking new potentials for high‐resolution acoustic imaging and ...
Xiao Guo +15 more
wiley +1 more source
A lightweight CNN-transformer hybrid architecture with channel attention for real-time hazardous acoustic event detection. [PDF]
Altayeva A, Omarov N.
europepmc +1 more source
The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie +20 more
wiley +1 more source
A Comparative Study of Caerin 1.1/1.9 and Calcium Hydroxide in the Treatment of Apical Periodontitis in Rats. [PDF]
Qin L +11 more
europepmc +1 more source
Autonomous High‐Throughput Characterization of Liquid‐Liquid Phase Behavior
This study introduces an automated dual modality platform, combining asymmetric capacitance deviation and multiangle turbidimetry, for high‐throughput characterization of liquid‐liquid phase behavior across chemically diverse fluid systems. The platform enables miscibility classification, resolution of phase separation kinetics and emulsion stability ...
Tarek Eid +3 more
wiley +1 more source
Audiomotor prediction errors drive speech adaptation even in the absence of overt movement. [PDF]
Parrell B +5 more
europepmc +1 more source
Pressure overload suppresses cardiomyocyte ZER1, weakening CRL2Zer1‐mediated DVL2 degradation and allowing DVL2 accumulation. Elevated DVL2 activates CaMKII‐HDAC4‐MEF2C signaling, drives fetal gene reactivation, and promotes pathological remodeling.
Mingchao Jiang +27 more
wiley +1 more source

