Results 131 to 140 of about 123,710 (270)

Self‐harm in individuals with substance use disorders: Predictive factors and risk model

Addiction, EarlyView.
Abstract Background and aims Substance use disorders are associated with an elevated risk of self‐harm. Currently, clinical and structured assessment of self‐harm risk typically relies on evidence from the general population samples. The aim of this study was to develop a risk model for self‐harm that incorporates predictors specific to individuals ...
Rongqin Yu, Derek K. Tracy, Julia Sinclair, Isabell Brikell, Paul Lichtenstein, Henrik Larsson, Seena Fazel   +6 more
wiley   +1 more source

Therapy after therapy: Entry rates into subsequent psychological treatment among patients receiving therapist‐guided internet‐delivered or face‐to‐face psychotherapy

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives Despite numerous psychotherapy trials, knowledge on service‐system efficiency in terms of return to treatment is limited, especially regarding internet‐delivered cognitive behavioural therapy (iCBT). We estimated the hazard ratio (HR) of subsequent psychological treatment over several years following the initial psychological ...
A. Plattonen, S. Mylläri, S. E. Saarni, T. Rosenström   +3 more
wiley   +1 more source

Extending reliability to intensive longitudinal data with the Kalman filter

British Journal of Mathematical and Statistical Psychology, EarlyView.
Abstract Reliability is central to how researchers approach measurement in standard, group‐based analyses of single‐time‐point data, yet this critical aspect is often overlooked in the analysis of repeated observations. Since its inception, reliability has been a between‐person concept, but we redevelop this notion for within‐person designs by ...
Michael D. Hunter
wiley   +1 more source

Thorncliffe Formation: A proglacial to subglacial lacustrine basin sequence, Greater Toronto Region, Canada

Boreas, EarlyView.
Map of Lower sediment (LS) thickness is a surrogate for the distribution of Thorncliffe Formation (TF) and ~75% of TF thickness from the slope of Niagara Escarpment east to Brighton. Inset images show the LS sequence at the Don Valleys brickyards (DVBY) and undeformed TF sand and gravel (~15 m) below Newmarket Till (NT) at sites L and Co.
David R. Sharpe, Charles E. Logan, Ross D. Knight, Andre J.‐M. Pugin   +3 more
wiley   +1 more source

Differential effects of ketamine enantiomers on EEG parameters including the gamma‐delta shift phenomenon

British Journal of Pharmacology, EarlyView.
Background and Purpose Ketamine consists of two enantiomers, (R)‐ketamine and (S)‐ketamine, which exhibit distinct pharmacological properties. Currently, only the (S)‐enantiomer has been approved for the treatment of major depressive disorder, whereas recent clinical studies have failed to demonstrate an antidepressant effect for (R)‐ketamine.
Szabolcs Koncz, Dóra Pothorszki, Noémi Papp, Donát Pál, György Bagdy   +4 more
wiley   +1 more source

Weaving Political Identities: Jean‐Luc Nancy, Empedocles, and (the Later) Plato

Constellations, EarlyView.
Benjamin Hutchens
wiley   +1 more source

PLGA‐particle‐based vaccine induces SARS‐CoV‐2‐specific antibody and T‐cell responses

British Journal of Pharmacology, EarlyView.
A novel coronavirus disease 2019 (COVID‐19) vaccine encapsulating recombinant severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) spike receptor binding domain (RBD) with the double stranded RNA (dsRNA) analogue Riboxxim induces robust systemic and respiratory T‐ and B‐cell responses in mice.
Dennis Horvath, Katharina Inholz, Dennis Mink, Alicia Madel, Julia Koerner, Reinhold Horlacher, Michael Basler   +6 more
wiley   +1 more source

FAK/SRC-JNK axis promotes ferroptosis via upregulating ACSL4 expression. [PDF]

Cell Death Dis
Qin J, Ma S, Wang J, Huang S, Luan J, He J, Hou G, Sun N, Zhang W, Gao M.   +9 more
europepmc   +1 more source

A novel selective stabilizer of the ryanodine receptor 2 prevents stress‐induced ventricular arrhythmias without impairing cardiac function

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Aberrant activation of type 2 ryanodine receptors (RyR2) causes lethal arrhythmias, such as catecholaminergic polymorphic ventricular tachycardia (CPVT). Developing drugs that suppress RyR2 hyperactivation may be key to novel arrhythmia treatments.
Nagomi Kurebayashi, Masami Kodama, Hana Inoue, Masato Konishi, Masami Sugihara, Takashi Murayama, Ryosuke Ishida, Koichiro Ishii, Shuichi Mori, Yukari Endo, Xi Zeng, Yukiko U. Inoue, Takayoshi Inoue, Satoru Noguchi, Hajime Nishio, Eri Nakashima, Norio Suzuki, Noriko Nakaya, Ryushi Sato, Yuya Otori, Ayuna Tsutsumi, Mirei Takahashi, Takayuki Oka, Haruo Ogawa, Kayoko Kanamitsu, Hiroyuki Kusuhara, Utako Yokoyama, Junko Kurokawa, Hiroyuki Kagechika, Takashi Sakurai   +29 more
wiley   +1 more source

Biochemical Characterization of a Kunitz-Type Protease Inhibitor From Mimosa regnellii and Its Effects on Melanoma Cell Viability and Angiogenesis. [PDF]

Chem Biodivers
Rabêlo LMA, Cardoso PHO, Nobre LTDB, Dos Santos PIM, Lucena SV, Serquiz RP, Bemquerer MP, Rocha HAO, Nader HB, Dos Santos EA, de Oliveira AS, Frihling BEF, Migliolo L.   +12 more
europepmc   +1 more source