Cyclic adenosine monophosphate (cAMP) is a key cellular second messenger. Adenylyl cyclase converts emissive isomorphic nucleoside triphosphates into fluorescent cAMPs. cthAMP displays unusually high brightness compared to thATP, its precursor, enabling real‐time monitoring of enzymatic reactions.
Deyuan Cong +3 more
wiley +2 more sources
Crushing Mechanics and Flour Properties of Wheat Under Different Graded Crushing Durations in a Blade Crusher. [PDF]
Zhang C, Hu J, Xu Q, Zhang H, Li R.
europepmc +1 more source
Investigating Potential Adverse Drug Reactions of Lisdexamfetamine Using Sequence Symmetry Analysis
ABSTRACT The prevalence of ADHD is increasing rapidly, and lisdexamfetamine is increasingly popular, but few studies investigate its safety. We performed a sequence symmetry analysis (SSA) using Danish register data to identify potential ADRs associated with lisdexamfetamine in 2013–2023.
Thomas Leth Jensen +8 more
wiley +1 more source
Surface display of co-stimulatory ligand B7H2 on engineered bacteria enhances tumor immunotherapy. [PDF]
Feng Q +6 more
europepmc +1 more source
Extending reliability to intensive longitudinal data with the Kalman filter
Abstract Reliability is central to how researchers approach measurement in standard, group‐based analyses of single‐time‐point data, yet this critical aspect is often overlooked in the analysis of repeated observations. Since its inception, reliability has been a between‐person concept, but we redevelop this notion for within‐person designs by ...
Michael D. Hunter
wiley +1 more source
Regulation of immune signal integration and memory by inflammation-induced chromosome conformation. [PDF]
Daniel B +8 more
europepmc +1 more source
We identify four distinct C5 inhibitory epitopes, including two novel antibodies that selectively block membrane attack complex (MAC) assembly while preserving C5 cleavage and C5a generation. These findings establish selective MAC inhibition as a new therapeutic strategy for complement‐mediated diseases.
Rebekah Sian Cooke +5 more
wiley +1 more source
Development of a Horseradish Peroxidase-Based Electrochemical Biosensor for Melatonin Detection. [PDF]
Trifan AG, Apetrei C.
europepmc +1 more source
Mental disorders in childhood or adolescence and subsequent comprehensive school achievement
Background Childhood mental disorders are associated with poorer school achievement, with potential negative long‐term socio‐economic consequences, but few large‐scale studies have examined this association, particularly the role of age at onset.
Yan Li +5 more
wiley +1 more source
First-Recorded Alcohol Use Disorder Diagnosis as an Ascertainment Outcome: Implications for GLP-1 Target Trial Emulations. [PDF]
Sung CH, Wei LC.
europepmc +1 more source

