Results 191 to 200 of about 44,344 (261)

Pan‐Cancer Analysis of the Immunomodulatory Roles and Prognostic Value of PDXP and Experimental Verification in SKCM

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Multiple public databases, including TCGA, GEO, and TARGET, were utilized to comprehensively analyze pyridoxal phosphatase (PDXP) expression profiles across 34 cancer types. We further explored the associations of PDXP expression with clinicopathological features, tumor immune microenvironment, genomic heterogeneity, functional signaling ...
Yingjian Hu, Xinzhu Zeng, Wei Cao, Jianhao Jiao, Yuan Zhao, Jun Wang   +5 more
wiley   +1 more source

Curcuminoids and Dimethoxycurcumin as Therapeutic Agents in Melanoma: Focus on Metastasis and Primary Care Integration

Cell Biochemistry and Function, Volume 44, Issue 10, October 2026.
ABSTRACT Melanoma is a type of skin cancer associated with the uncontrolled growth of melanocytes, the pigment‐producing cells. This type of skin cancer continues to be a major concern owing to its strong tendency to spread. Melanoma progression is influenced by the activation of various signalling pathways, such as PI3K/AKT/mTOR, MAPK/ERK, and Wnt/β ...
Tivoli Visser, Charlise Basson, Priyesh Bipath, Yvette Nkondo Hlophe   +3 more
wiley   +1 more source

Increasing hydrophobicity in poly(amino acid) adjuvants elicits potent and durable anti-tumor immunity <i>via</i> coordinated cellular and humoral responses. [PDF]

Bioact Mater
Qin C, Xin H, Wei Q, Xiao Q, Yang G, Ding J.   +5 more
europepmc   +1 more source

β2 Adrenoceptor Signaling Modulates Myoblast Differentiation via miR‐374b‐5p/GSK3β and miR‐326‐3p/Tnfrsf11a Axes

Cell Biology International, Volume 50, Issue 10, October 2026.
ABSTRACT Myoblast differentiation is a crucial step of skeletal muscle regeneration and is impaired in the absence of the β2 adrenoceptor (ADRβ2). Since miR‐374b and miR‐326 regulate cell differentiation, this study investigated if ADRβ2 regulates myoblast differentiation via miR‐374b‐5p and miR‐326‐3p. Primary myoblasts from ADRβ2 knockout (β2KO) mice
Tatiana E. Koike, Cesar S. Fuziwara, Audrei R. Santos, Fernanda V. B. Delpupo, Tábata L. Nascimento, Andrei Rozanski, Marcelo G. Pereira, Patrícia C. Brum, Edna T. Kimura, Thomas A. Rando, Elen H. Miyabara   +10 more
wiley   +1 more source

Cancer immunotherapy targeting murine myeloid cells requires endosomal pattern recognition. [PDF]

Nat Commun
Pan Y, Pei S, Liang H, Westberg K, Nitschke L, Chen X, Yu Y, He N, Lin Q, Lei L, Gisterå A, Hartman J, Ravetch JV, Mak TW, McGaha TL, Karlsson MCI.   +15 more
europepmc   +1 more source

Engineering Tin Foam Electrodes for High‐Rate CO2 Reduction: A Pathway to Sustainable Formic Acid Production

ChemElectroChem, Volume 13, Issue 19, 1 October 2026.
Highly porous Sn foam electrodes prepared by dynamic hydrogen bubble template exhibit high selectivity for CO2 reduction to formic acid. No decline of catalytic activity or selectivity, or morphological modifications were observed after long‐term electrolysis operating at high current densities.
Andrea Antonello, Ermanno Pierobon, Marco Fantin, Giulia Stefan, Abdirisak A. Isse   +4 more
wiley   +1 more source

Cofilin1-driven cytoskeletal remodeling modulates pan-cancer CD8⁺ T cell immunotherapy responses. [PDF]

Cell Rep Med
Li L, Chao Z, Li J, Ma C, Zhang R, Zhang J, Luo J, Horne D, Wang Y, Hao X, Zhang C, Guo X, Ma S, Peng H, Hu Z, Yuh B, Wei GH, Yang X, Zhang Q, Wang B, Zhang X, Liu Z, Zhang Z, Lan P, Wang Z.   +24 more
europepmc   +1 more source

Deep Learning‐Based Quantification of Spontaneous Pain Behaviours in Mice

European Journal of Pain, Volume 30, Issue 9, October 2026.
ABSTRACT Background Accurate evaluation of pain‐related behaviours in rodent models is crucial for elucidating pain mechanisms and assessing the efficacy of novel analgesic compounds. Traditional nociceptive assays primarily measure evoked responses, which have limited translational relevance since spontaneous pain is the predominant symptom in pain ...
Michele Zanoletti, Elisa Bellantoni, Lídia Pombo Gomes, Maria Luiza Quadros dos Santos, Daniel Souza Monteiro de Araújo, Gaetano De Siena, Sabrina Qader Kudsi, Romina Nassini, Marco Laurino, Francesco De Logu   +9 more
wiley   +1 more source

Multifunctional Hybrid Gels Containing Silver Nanoparticles, Gold Nanorods, and Protoporphyrin IX for Synergistic Photothermal-Photodynamic Therapy. [PDF]

ACS Omega
Neves RCS, de Oliveira AL, Araújo SS, de Oliveira PL, Brasileiro-Vidal AC, Alves IBV, Silva JYR, Luz LL, T Jesus L, Freire RO, A Junior S.   +10 more
europepmc   +1 more source