Results 211 to 220 of about 123,710 (270)

Development of CAR Exosomes Targeting FAP for the Treatment of Intrauterine Adhesion

Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
ABSTRACT Engineered extracellular vesicles (EVs) have emerged as promising cell‐free platforms for immunomodulation and tissue repair. In this study, we generated EVs derived from chimeric antigen receptor (CAR) T cells targeting fibroblast activation protein (FAP) and investigated their biological and therapeutic functions.
Wenyan Fu, Kewen Qian, Hongru Ai, Yitan Zou, Yaping Zhou, Ruixue Mao, Jian Zhao, Changhai Lei, Shi Hu   +8 more
wiley   +1 more source

Chemotherapeutic Spherical Nucleic Acids. [PDF]

ACS Nano
Luo T, Kim YJ, Han Z, Hwang J, Kumari S, Mayer V, Cushing A, Romero RA, Mirkin CA.   +8 more
europepmc   +1 more source

GOES‐R Series X‐Ray Sensor (XRS): 2. On‐Orbit Measurements and Calibrations

Journal of Geophysical Research: Space Physics, Volume 131, Issue 5, May 2026.
Abstract An X‐Ray Sensor (XRS) has been onboard each of the National Oceanic and Atmospheric Administration (NOAA) Geostationary Operational Environmental Satellites (GOES) since 1975. XRS measures full‐disk soft X‐ray irradiance in two wavelength bands, 0.05–0.4 nm and 0.1–0.8 nm.
Janet L. Machol, Stefan M. Codrescu, Courtney L. Peck, Elysia S. Lucas, James F. Mothersbaugh III, Thomas N. Woods, Ann Marie Mahon, James Negus, Donald L. Woodraska, Thomas D. Eden Jr., Francis G. Eparvier, Andrew R. Jones, Brooke Kotten, Laurel A. Rachmeler, Andrew C. Wilson, Brian T. Kress, Juan V. Rodriguez, Rodney A. Viereck   +17 more
wiley   +1 more source

A protective cGAMP-mediated anti-tumor immune response can proceed without LRRC8/VRAC channels. [PDF]

J Biol Chem
Thöne FMB, Polovitskaya MM, Höpken UE, Rehm A, Jentsch TJ.   +4 more
europepmc   +1 more source

Brain Aging Mediating Heart Imaging‐Derived Phenotypes and Mental and Nervous System Disorders

Aging Cell, Volume 25, Issue 5, May 2026.
Using heart and brain imaging from 33,573 UK Biobank participants, we establish a clear association between brain aging and cardiac structural changes. In addition, we uncover several potentially modifiable lifestyle and environmental factors that contribute to mental and nervous system disorders, mediated through alterations in cardiac structure and ...
Zairen Zhou, Wenjing Su, Yuna Li, Bei Zhang, Fang Lan, Dawei Lin, Jin‐Tai Yu, Jianfeng Feng, Yifei Jin, Peng Ren, Wei Cheng   +10 more
wiley   +1 more source

A selective RPL15 PROTAC degrader enhances anti-PD-1 immunotherapy in a murine melanoma tumor model. [PDF]

Oncogene
Takahashi R, Yamamoto K, Toya H, Shoji H, Kawanishi K, Momosaki K, Yabe M, Takashima K, Muromoto R, Ichikawa S, Matsuda T, Kitai Y.   +11 more
europepmc   +1 more source

Bleeding Disorders in Children With Genetic Diseases: A Narrative Review

Acta Paediatrica, Volume 115, Issue 5, Page 1015-1024, May 2026.
ABSTRACT Aim The lack of data on bleeding risk assessment in children with genetic diseases is concerning given their increased care needs and risk of haemorrhagic complications compared to the general population. Identification of haemostatic disorders is crucial for implementing preventive measures and mitigating bleeding risk.
Raphaelle Cagol, Mariam Sbeity Barakat, Marjolaine Willems, Tasnime Akbaraly, Biron‐Andreani Christine, Isabelle Diaz, Alexandre Theron   +6 more
wiley   +1 more source

mTORC2 inhibition reduces tumor burden via STAT1 activation and enhanced response to anti-PD-L1 therapy. [PDF]

Cell Death Dis
Gschwendtner A, Schütz B, Mirea MA, Eckel O, Kepa MZ, Fritsch SD, Oberle R, Weichhart T, Hengstschläger M, Mikula M.   +9 more
europepmc   +1 more source

Gamma‐irradiated Newcastle disease virus: an alternative inactivated oncolytic virotherapy

Immunology &Cell Biology, Volume 104, Issue 5, Page 473-484, May‐June 2026.
To overcome biological risks associated with using live NDV as an oncolytic therapy, we developed gamma‐NDV as a safer alternative. Using a murine model for skin cancer, we show that intratumor administration of gamma‐NDV outperformed live‐NDV in terms of reducing tumor growth and improving overall animal survival. Abstract Newcastle disease virus (NDV)
Eve V Kennedy, Yimin Chuah, Amal H Mostafa, Chloe J Gates, Jade Foeng, Todd S Norton, Shaun R McColl, Iain Comerford, Justin B Davies, Farhid Hemmatzadeh, Mohammed Alsharifi   +10 more
wiley   +1 more source

Integrating image processing and machine learning for phase specific estimation of Manning roughness coefficient in furrow irrigation. [PDF]

Sci Rep
Rad HR, Ebrahimian H, Liaghat A, Omid M, Khalaji F, Arani MS.   +5 more
europepmc   +1 more source