Results 181 to 190 of about 142,938 (289)

Accurate Identification of Protein Binding Sites for All Drug Modalities Using ALLSites

Advanced Science, EarlyView.
ALLSites is a unified sequence‐based framework for identifying proteome‐wide binding sites across all drug modalities. It integrates a gated convolutional network with a transformer architecture to capture residue interactions directly from the sequence.
Minjie Mou, Mingkun Lu, Zhimeng Zhou, Yanlin Ren, Xinyuan Yu, Ziqi Pan, Yuan Zhou, Hao Yang, Lingyan Zheng, Shukai Gu, Yang Zhang, Wei Hu, Fengcheng Li, Haibin Dai, Feng Zhu   +14 more
wiley   +1 more source

Machine and Deep Learning for Detection of Moderate-to-Vigorous Physical Activity From Accelerometer Data: Systematic Scoping Review.

Interact J Med Res
Zi Y, van de Ven SR, de Geus EJ, Chen P.
europepmc   +1 more source

Artificial Intelligence Applications in Chronic Obstructive Pulmonary Disease: A Global Scoping Review of Diagnostic, Symptom-Based, and Outcome Prediction Approaches. [PDF]

Biomedicines
Pinheira A, Casal-Guisande M, Represas-Represas C, Torres-Durán M, Comesaña-Campos A, Fernández-Villar A.   +5 more
europepmc   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

Hybrid feature selection with novel deep learning model for COVID-19 risk prediction. [PDF]

Sci Rep
P GS, Kathiravan M, Shanthi S, Alqahtani MS, Abbas M, Ayalew F.   +5 more
europepmc   +1 more source

Evaluation metrics (accuracy, precision, recall, F1-score) comparing the proposed model with other models (related to Table 4).

Islam Zada (21755819), Esraa Omran (6392693), Salman Jan (21755822), Hessa Alfraihi (21755825), Seetah Alsalamah (21755828), Abdullah Alshahrani (9458515), Shaukat Hayat (14634285), Nguyen Phi (21755831)   +7 more
openalex   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

Specificity (SP), sensitivity (SN), F1-Score, Matthews correlation coefficient (MCC), and accuracy (ACC) for classification of nuclei types.

Anjir Ahmed Chowdhury (21696531), S M Hasan Mahmud (21696534), Md Palash Uddin (13473853), Seifedine Kadry (8713629), Jung-Yeon Kim (410325), Yunyoung Nam (2559640)   +5 more
openalex   +1 more source

Bidirectional Photoadaptive Organic Heterojunction Synaptic Transistors for Accurate Image Recognition in Machine Vision Systems

Advanced Science, EarlyView.
Bidirectional photoadaptive organic synaptic phototransistors are developed using complementary n–n and n‐p heterojunctions. These devices enable intelligent in‐sensor processing, markedly enhancing image contrast and edge features under adverse lighting, and achieve a recognition accuracy of 97.4% within ten training cycles for machine vision ...
Di Xue, Hongyu Liu, Yingying Zhang, Feng Ding, Jie Lu, Yao Yin, Zi Wang, Jianlong Xu, Lifeng Chi, Lizhen Huang   +9 more
wiley   +1 more source

Deep recurrent models for forecasting infectious diseases. [PDF]

Front Public Health
Alzamel M.
europepmc   +1 more source