Background and Purpose Spinal muscular atrophy (SMA) is a motor neuron disease caused by SMN1 gene loss, leading to reduced survival motor neuron (SMN) protein and progressive motor neuron degeneration. Although SMN‐restoring therapies improve outcomes, residual disease burden and non‐curative efficacy underscore the need for complementary treatments ...
Fernanda C. Cardoso +3 more
wiley +1 more source
Integration of hereditary thrombophilia data and polygenic risk scores into prognostic models improves differential diagnosis of CTEPH. [PDF]
Kubkin Y +12 more
europepmc +1 more source
ABSTRACT Artificial intelligence (AI) is increasingly reshaping extracurricular language learning, yet little is known about how young learners construct motivation when using AI to learn less commonly taught foreign languages. This study investigates primary school students' motivational typologies and the factors related to these configurations in AI‐
Xun Lu, Nanlan Pei
wiley +1 more source
Experiment-Based Optimization of LED Spectral Irradiance Ratios for Enhancing Biomass, Secondary Metabolite, and Essential Oil Yields and Compositions of <i>Ocimum</i> × <i>africanum</i> Lour. Under Controlled Environmental Conditions. [PDF]
Chu HTT +10 more
europepmc +1 more source
ABSTRACT Background Hemophilia A, an X‐linked bleeding disorder caused by pathogenic variants in the F8 gene, requires precise genetic diagnosis for optimal management. Conventional stepwise sequence and copy number variation (CNV) analyses are time‐consuming and may leave some cases unresolved.
Enise Avci Durmusalioglu +13 more
wiley +1 more source
Characterisation of seminal plasma-derived mediators involved in PMN evasion of ram spermatozoa <i>in vitro</i>. [PDF]
Warr S +6 more
europepmc +1 more source
Genetically Encoded Pentafluorophenylalanine Enables Quantitative Probing of Local Protein Malleability by 19F NMR. [PDF]
Paul N +13 more
europepmc +1 more source
Synthesis of the Phospha-Wittig Reagent Me<sub>3</sub>P = P(C<sub>2</sub>F<sub>5</sub>) and Generation of a Phospanyl-Wittig Derivative Me<sub>3</sub>P = C(CF<sub>3</sub>)P(C<sub>2</sub>F<sub>5</sub>)F. [PDF]
Hartmann L +7 more
europepmc +1 more source
Development and nutritional evaluation of an extruded grain amaranth-instant porridge as a supplementary food for children under five with moderate acute malnutrition. [PDF]
Mwikwabe AS +3 more
europepmc +1 more source

