Results 71 to 80 of about 1,231,086 (256)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

La Medicina Interna ospedaliera: tra complessità ed intensità assistenziale verso una medicina sostenibile

Italian Journal of Medicine, 2014
La Medicina Interna ospedaliera: tra complessità ed intensità assistenziale verso una medicina sostenibile M. Campanini La complessità dei pazienti ricoverati nei reparti ospedalieri di Medicina Interna: di che cosa stiamo parlando? R. Nardi, D. Borioni,
Guest Editors: M. Campanini, A. Fontanella, C. Nozzoli, A. Mazzone, R. Nardi   +4 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

On growth order of solutions of differential equations in a neighborhood of a branch point [PDF]

Математичні Студії, 2013
Let $M_k$ be {the} set of $k$-valued meromorphic in$G={zcolon r_0leqslant |z|}$ functions with {a}~branch point of order$k-1$ {at} $infty$; let $E_ast$ be a set of circles {with finite} sum of radii.
A. Z. Mokhonko, A. A. Mokhonko
doaj  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Retrieval of the Fraction of Radiation Absorbed by Photosynthetic Components (FAPAR_green) for Forest Using a Triple-Source Leaf-Wood-Soil Layer Approach

Remote Sensing, 2019
The fraction of absorbed photosynthetically active radiation (FAPAR) is generally divided into the fraction of radiation absorbed by the photosynthetic components ( F A P A R g r e e n ) and the fraction of radiation absorbed by the non ...
Siyuan Chen, Liangyun Liu, Xiao Zhang, Xinjie Liu, Xidong Chen, Xiaojin Qian, Yue Xu, Donghui Xie   +7 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Avaliação da Funcionalidade dos Membros Superiores, Qualidade de Vida e Fadiga no Pós-operatório de Mulheres com Câncer de Mama em um Hospital de Referência na Amazônia

Revista Brasileira de Cancerologia
Introdução: O câncer de mama gera impactos significativos na funcionalidade dos membros superiores (MMSS) em razão do tratamento e suas complicações. Objetivo: Avaliar a funcionalidade dos MMSS, qualidade de vida e fadiga de mulheres com câncer de mama ...
Myara Cristiny Monteiro Cardoso, Rayssa da Silva Araújo, Jaqueline Pinheiro da Silva, Rayane de Nazaré Monteiro Brandão, Saul Rassy Carneiro   +4 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source