Results 141 to 150 of about 82,602 (277)

Perforation Enhances Sound Insulation in Plate Lattice Metamaterials

Small, EarlyView.
Herein, perforations are engineered into face‐centered cubic plate lattice metamaterials to convert normally detrimental openings into acoustically active features. Experiments, finite‐element analyses, and a reduced‐order transfer‐matrix model show that selected perforation geometries activate Helmholtz‐like and cavity‐mediated resonances, enhancing ...
Jing Heng Tan, Chenxu Liu, Zhendong Li, Xinwei Li   +3 more
wiley   +1 more source

A Dual‐Frequency Sensitivity Model for Optical Fibre Ultrasonic Sensors in Power Transformer Partial Discharge Detection

High Voltage, EarlyView.
ABSTRACT The detection of partial discharges (PD) on the power transformer tank demands higher sensitivity in ultrasonic detection. To target the detection frequency band for sensor optimisation and enhance sensitivity, this paper presents a dual‐frequency sensitivity model for optical fibre ultrasonic sensors.
Sihan Wang, Jihang Sun, Jialin Wang, Bin Wei, Guoming Ma   +4 more
wiley   +1 more source

On the Conceptual Overstretch of Weaponized Interdependence in Lithium and Rare‐Earth Element Markets

Global Policy, EarlyView.
ABSTRACT This paper critically examines the conceptual overstretch of weaponized interdependence (WI) in analyses of China's dominance over lithium and rare‐earth element (REE) markets. Although WI has become a central framework for interpreting EU–China economic relations, its application to raw materials often extends beyond the theory's original ...
Lucas Miailhes
wiley   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Identification of Copy Number Variants as a Suspected Cause of Cerebral Small Vessel Disease

Clinical Genetics, EarlyView.
Whole‐exome sequencing of 111 patients with suspected familial cerebral small vessel disease (CSVD) identified novel copy number variants in four patients across NOTCH3, LMNB1, and COL4A2, using bioinformatic and molecular techniques. These validated CNVs suggest structural variation is an underrecognized potential causal contributor to monogenic CSVD ...
Solomon K. Guyler, Neven Maksemous, Rodney A. Lea, Robert A. Smith, Heidi G. Sutherland, Lyn R. Griffiths   +5 more
wiley   +1 more source

SGLT2 Inhibitors and Cardiovascular Outcomes in Patients With Fabry Disease: Observations From a Federated Research Network

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background and Aim Fabry disease (FD) is frequently complicated by renal impairment and cardiovascular events; however, evidence on sodium–glucose cotransporter‐2 inhibitors (SGLT2i) in this population is scarce. Accordingly, we assessed the association between SGLT2i exposure and cardiovascular outcomes in adults with FD. Methods We conducted
Leandra Serio, Michele Rossi, Amir Askarinejad, Enrico Tartaglia, Tommaso Bucci, Enrica Marrone, Dinesh K. Kalra, Claudio Ferri, Gregory Y. H. Lip   +8 more
wiley   +1 more source

Clinical manifestations, diagnosis, and management of renal involvement in Fabry disease. [PDF]

Ren Fail
Guo W, Bi J, Ji P, Xie Y.
europepmc   +1 more source

Molecular dynamics simulations elucidate the misfolding mechanisms of secretion‐defective pancreatic lipase variants

The FEBS Journal, EarlyView.
Misfolding mutations in pancreatic lipase have been identified as potential contributors of chronic pancreatitis, an inflammatory disease of the human pancreas. Here, we describe the effect of these misfolding mutations on pancreatic lipase structure using molecular dynamics simulations and structural modeling.
Gyula Hoffka, András Szabó
wiley   +1 more source

Fabry disease: Enfermedad de fabry

, 2018
RESUMEN La enfermedad de Fabry es una enfermedad de depósito lisosomal causada por la deficiencia de la enzima alfa galactosidasa A, con patrón de herencia ligado al cromosoma X. El cuadro clínico tiene una variedad de síntomas y signos; y se han descrito una variante clínica clásica y variantes clínica no clásica como la renal o cardíaca.
openaire   +1 more source

Impaired motor unit profile in Fabry disease: A quantitative electrophysiological study. [PDF]

Clin Neurophysiol Pract
Gunduz A, Akkan Suzan A, Dinçer MT, Özcan ŞG, Seyahi N.   +4 more
europepmc   +1 more source