Results 161 to 170 of about 60,446 (292)
British Journal of Pharmacology, EarlyView.Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley +1 more source
The FEBS Journal, EarlyView.Misfolding mutations in pancreatic lipase have been identified as potential contributors of chronic pancreatitis, an inflammatory disease of the human pancreas. Here, we describe the effect of these misfolding mutations on pancreatic lipase structure using molecular dynamics simulations and structural modeling.
Gyula Hoffka, András Szabó
wiley +1 more source
Beyond the Adult Mind: A Developmental Framework for Predictive Processing in Infancy
Topics in Cognitive Science, EarlyView.Abstract Predictive Processing has been proposed as the single unifying computation underlying all of cognition, and proponents argue that all psychological phenomena can be explained as consequences of this principle. This theoretical framework has inspired many cognitive scientists and neuroscientists, but it currently has no developmental mechanism ...
Emma K. Ward +4 more
wiley +1 more source
Interindividual variability in static apnoea performance is partly explained by genetic factors
Experimental Physiology, EarlyView.Abstract A large interindividual variability exists in maximal apnoea duration and the physiological adjustments that occur during apnoea. Although a few genes have been found to be associated with some of the cardiovascular responses during apnoea, the extent to which genetic and environmental factors contribute to individual differences in apnoea ...
Anastasios Makris +5 more
wiley +1 more source
Angiokeratoma: decision-making aid for the diagnosis of Fabry disease
, 2012 Isolated angiokeratomas are common benign cutaneous lesions, generally deemed unworthy of further investigation. In contrast, diffuse angiokeratomas should alert the physician to a possible diagnosis of Fabry disease, a rare X-linked lysosomal storage
the Interdisciplinary Study Group on Fabry Disease +13 more
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Case Report: Is it COPD? It is Fabry disease: a case in which bronchodilators were briefly used but not continued, prioritizing enzyme replacement therapy. [PDF]
Front PharmacolLi Y +8 more
europepmc +1 more source
Neighborhood Attributes Desired by Doylestown Homeowners
, 2004 Debate over land development continues to be an issue of dissension between developers and designer. Of particular contention is the issue of neighborhood design.
Fabry, Suzanna
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Targeting fibrosis in the treatment of lower urinary tract dysfunction
The Journal of Pathology, Volume 269, Issue 4-5, Page 493-503, August 2026.Abstract Benign prostatic hyperplasia (BPH) is a widely prevalent age‐associated disease that is the main contributor to lower urinary tract dysfunction (LUTD) in aging men. Although prostate fibrosis has been recognized as a contributor to BPH pathophysiology, there are not any clinically available therapeutics that target this aspect of disease ...
Ajinkya R Limkar +6 more
wiley +1 more source
Modeling Fabry nephropathy: insights from experimental systems towards precision nephrology. [PDF]
Dis Model MechElsaid H +4 more
europepmc +1 more source
Effectiveness of Family Interventions in Bipolar Disorder: A Systematic Review
Bipolar Disorders, Volume 28, Issue 5, August 2026.ABSTRACT Introduction Bipolar disorder (BD) is a chronic mental health condition characterized by extreme mood swings, which significantly affects both the individual and their family system. Given the psychosocial impact of BD on families, family interventions (FI) have emerged as a promising approach to improve treatment outcomes.
Madeha Umer +8 more
wiley +1 more source