Results 101 to 110 of about 3,226,379 (308)
La linea e la rete. La costruzione della conoscenza in un Quartetto di Haydn
Analisi del Quartetto Op. 77/1 di F. J.
LA FACE, GIUSEPPINA
core
Toxicomania e posições subjetivas: uma dialética entre o prazer e o gozo
A literatura evidencia que o fenômeno da toxicomania não se deixa reduzir a qualquer classificação ou estrutura psicopatológica, pois oscila entre a neurose, a perversão e a psicose.
Ana Paula Paes de Paula
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
This is a collection of 10 Trevor Sewell songs recorded at perhaps one of the most iconic studios in the world. Recorded in 2014 at Capitol Records studio in Hollywood the album was a completely spontaneous performance album featuring no overdubs.
Sewell, Trevor
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A transição de contribuidor individual para líder: a experiência vivida pelo professor universitário
http://dx.doi.org/10.5007/1983-4535.2012v5n1p145 Este trabalho objetiva compreender o processo de transição do contribuidor individual (professor) para líder (reitor ou pró-reitor) em universidades.
Fabiula Meneguete Vides da Silva +1 more
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Finding Aid for Wesley Face Personal Papers, 1985-1991
Face earned his Bachelor of Science in industrial education and history in 1951. He received a Master of Science in industrial education in 1956 from Stout, and he received his Doctor of Education degree in 1963 from the University of Illinois. He taught
Face, Wesley
core
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

