Results 101 to 110 of about 4,136,812 (254)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

A transição de contribuidor individual para líder: a experiência vivida pelo professor universitário

Revista Gestão Universitária na América Latina, 2012
http://dx.doi.org/10.5007/1983-4535.2012v5n1p145   Este trabalho objetiva compreender o processo de transição do contribuidor individual (professor) para líder (reitor ou pró-reitor) em universidades.
Fabiula Meneguete Vides da Silva, Cristiano José Castro de Almeida Cunha   +1 more
doaj  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Mass of the parapharyngeal space: A tumor with a surgical challenge

Advances in Oral and Maxillofacial Surgery, 2023
Mohammed Laachoubi, Youssef Oukessou, Sami Rouadi, Reda Abada, Mohamed Roubal, Mohamed Mahtar   +5 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

La Musica tra conoscere e fare

, 2011
Il volume contiene una serie di tredici contributi di musicologi (G. La Face Bianconi; L. Bianconi; A. Chegai; R. Pozzi; E. Pasquini; S. Melis;G. Pagannone; C. Cuomo: M. R. De Luca), etnomusicologi (N. Staiti), musicisti (A. Solbiati; P.
La Face, G., Scalfaro, A.
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Impactos do estágio curricular não obrigatório sobre o desempenho acadêmico entre alunos de ciências econômicas: um estudo para a universidade federal de goiás

RACE: Revista de Administração, Contabilidade e Economia
A prática do estágio deve ser entendida como um complemento e não como algo rival à formação do estudante. Diante disso, o presente artigo tem por objetivo analisar os efeitos da realização de atividades de estágio curricular não obrigatório no ...
Sandro Eduardo Monsueto, Adriana Moura Guimarães, Alicia Araújo Amaral de Oliveira   +2 more
doaj  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source