Results 111 to 120 of about 25,067,764 (296)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The Grotesque of Luigi Chiarelli: La maschera e il volto.

open access: yesCuadernos de Filología Italiana, 2003
It deals with the way to look into the meaning of grotesque and differentiate it from humour, tragedy and satire and illustrates the coexistence of all these elements regarding grotesque.
Ana Martínez-peñuela
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Breve historia de la Red FACE [PDF]

open access: yes
La Red de Facultades de Ciencias Económicas del Norte Argentino (Red FACE) nació como respuesta a la necesidad de colaboración académica en una región rica en diversidad cultural y con desafíos económicos significativos.
Mura, Raúl   +2 more
core  

Mount Currie instrumental enrichment workshop

open access: yes, 1994
Production material features part of a multi-day workshop for teachers and parents on Instrumental Enrichment (FIE) conducted by Lorna Wánosts’a7 Williams in Mount Currie.
Face to Face Media
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Interview with Lorna Wánosts’a7 Williams, Rosa Andrew, and Susan Nelson

open access: yes, 1993
Production material centres around an interview conducted with Lorna Wánosts’a7 Williams, Rosa Andrew, and Susan Nelson in Mount Currie. In tape 1, Wánosts’a7 discusses her experience as a student at St.
Face to Face Media
core   +1 more source

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