Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Cerebral responses to famous face recognition as a potential functional biomarker of mild cognitive impairment. [PDF]
Koeda M, Ikeda Y, Okubo Y, Tateno A.
europepmc +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Low-resolution driver face recognition based on super-resolution and triplet loss. [PDF]
Zhang Z, Sun B, Liang J, He H, Qiao D.
europepmc +1 more source
Face Recognition Based on Wavelet Packet Coefficients and Radial Basis Function Neural Networks
T. Kathirvalavakumar +1 more
openalex +2 more sources
MODELING A SECURE EXAM MANAGEMENT SYSTEM (SEMS) FOR MOBILE ENVIRONMENT BASED ON FACE RECOGNITION AND GPS TECHNIQUES [PDF]
Hervé B. Olou, Eugène C. Ezin
openalex +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Efficient Privacy-Preserving Face Recognition Based on Feature Encoding and Symmetric Homomorphic Encryption. [PDF]
Zhou L, Li Q, Zhu H, Zhou Y, Wu H.
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source

