Results 31 to 40 of about 276,420 (304)

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Schedule of factors influencing access to psychiatric treatment in persons with schizophrenia: Validity and pilot testing

open access: yesIndian Journal of Psychological Medicine, 2013
Background : A substantial proportion of patients with severe mental disorders remain untreated in India. Qualitative research has highlighted the complex interplay of multiple factors that preclude schizophrenia patients in rural Indian settings from ...
K Shanivaram Reddy   +7 more
doaj   +1 more source

KUESIONER PERSEPSI CONTENT VALIDITY /FACE VALIDITY UNTUK REMAJA TUNANETRA

open access: yesJurnal Pendidikan Olahraga, 2022
Penelitian Delphi ini tujuannya adalah untuk mengetahui content/face validity dari persepsi diri, persepsi orang tua, dan kuesioner metaperception pada remaja penyandang tunanetra. Sampel berjumlah dua puluh empat termasuk ahli dari 4 kategori: (1) guru yang mengajar penyandang tunanetra disekolah, guru penjas adaptif dan guru umum yang berjumlah enam ...
Ibnu Sina, Ahmad Yani, Dena Widyawan
openaire   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Evaluation of content validity and face validity of secondary school Islamic education teacher self-assessment instrument

open access: yesCogent Education
This study aims to test the content and face validity of Secondary School Islamic Education Teacher Self-Assessment Instrument (SSIET-SAI) using Content Validity Ratio (CVR), Content Validity Index (CVI) and Cohen Kappa Index (CKI) analysis.
Azwani Masuwai   +2 more
doaj   +1 more source

A novel ex vivo perfusion-based mandibular pig model for dental product testing and training

open access: yesBMC Oral Health, 2023
Background A translational ex vivo perfusion-based mandibular pig model was developed as an alternative to animal experiments, for initial assessment of biomaterials in dental and maxillofacial surgery and training.
Machteld van Erk   +4 more
doaj   +1 more source

Development and validation of a social impact questionnaire for household food waste

open access: yesMethodsX, 2023
This exploratory study was conducted to develop and validate an instrument for measuring the social impact of food waste at the household level. A mixed methodology was employed, commencing with a qualitative approach through in-depth interviews and ...
Yayuk Farida Baliwati   +4 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

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