Results 71 to 80 of about 815,043 (337)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Identification of Body Behaviors and Facial Expressions Associated with Induced Orthopedic Pain in Four Equine Pain Scales

open access: yesAnimals, 2020
Equine orthopedic pain scales are targeted towards horses with moderate to severe orthopedic pain. Improved assessment of pain behavior and pain-related facial expressions at rest may refine orthopedic pain detection for mild lameness grades.
Katrina Ask   +4 more
doaj   +1 more source

Similarity index for intuitive assessment of three-dimensional facial asymmetry

open access: yesScientific Reports, 2019
Evaluation of facial asymmetry generally involves landmark-based analyses that cannot intuitively assess differences in three-dimensional (3D) stereoscopic structures between deviation and non-deviation sides.
S. Kwon   +6 more
semanticscholar   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Quantifying Perceived Facial Asymmetry to Enhance Physician–Patient Communications

open access: yesApplied Sciences, 2021
In cosmetic surgery, bridging the anticipation gap between the patients and the physicians can be challenging if there lacks objective and transparent information exchange during the decision-making and surgical process.
Shu-Yen Wan, Pei-Ying Tsai, Lun-Jou Lo
doaj   +1 more source

On the analysis of EEG power, frequency and asymmetry in Parkinson's disease during emotion processing [PDF]

open access: yes, 2014
Objective: While Parkinson’s disease (PD) has traditionally been described as a movement disorder, there is growing evidence of disruption in emotion information processing associated with the disease.
Ibrahim, Norlinah Mohamed   +8 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The effect of smiling on facial asymmetry in adults: a 3D evaluation

open access: yesAustralasian Orthodontic Journal, 2015
Mild resting facial asymmetry exists in clinically symmetrical faces, but the effect of smiling on the magnitude of overall facial asymmetry in adults has not been assessed.
Darby Laura J.   +4 more
doaj   +1 more source

Preoperative Anatomical Variables Affecting the Outcome of Surgical Correction in Class III Face Asymmetry

open access: yesApplied Sciences, 2023
Objective: The study investigated the preoperative anatomical variables that affect the outcome of surgical correction in patients with Class III facial asymmetry.
Yi-Ting Li   +3 more
doaj   +1 more source

New technologies in rhinoplasty : a comprehensive workflow for computer-assisted planning and execution [PDF]

open access: yes, 2019
Rhinoplasty in facial cleft patients is among the most challenging types of reconstructive facial surgery due to its variability Advances in 3-dimensional imaging enable improved preoperative assessment in rhinoplasty.
Codazzi   +7 more
core   +1 more source

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