Results 151 to 160 of about 781,361 (246)

Tailored Amino Acid Treatment for Pediatric Patients With Mitochondrial Aminoacyl‐tRNA Synthetase Deficiencies

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Aminoacyl‐tRNA synthetases (ARSs) facilitate the loading of transfer RNAs with their cognate amino acids in the cytosol (ARS1), mitochondria (ARS2), or both (dual ARS). ARS deficiencies are clinically heterogeneous and can cause severe, occasionally fatal disease.
I. J. J. Muffels   +21 more
wiley   +1 more source

Impact of Proposed Medicare Policy Changes for Botulinum Toxin Coverage on Hemifacial Spasm and Facial Dystonia

open access: yesFacial Plastic Surgery & Aesthetic Medicine
Alexander J. Barna   +5 more
semanticscholar   +1 more source

Obsessive–Compulsive Disorder: Comorbidity, Biomarkers, Circuits, and Treatment Strategies

open access: yesMedComm, Volume 7, Issue 11, November 2026.
OCD has a high comorbidity with other psychiatric conditions, among which anxiety is the most frequent one. The shared genetic biomarkers and common neural circuits underlying the co‐occurrence of OCD and anxiety pave a new path for understanding the pathogenic mechanism of OCD and suggest tailored and integrative treatment therapies for OCD from the ...
Xiao‐Yang Zhang   +9 more
wiley   +1 more source

Neurodegenerative Diseases: Epidemiology, Risk Factors, Classification, Pathophysiology, Clinical Features, Diagnosis, and Therapeutic Strategies

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He   +4 more
wiley   +1 more source

Suspected hyperthyroidism‐associated myoclonus in a cat

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 10‐year‐old, male, neutered domestic shorthair cat presented with a 2‐week history of progressively worsening myoclonic jerks predominantly involving the head. Jerks were continuous and marked at rest, but became less intense during activity.
Magdalena Maria Dyrka   +5 more
wiley   +1 more source

Olanzapine for the Prevention and Treatment of ICU Delirium: Protocol for a Systematic Review With Meta‐Analysis

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 10, November 2026.
ABSTRACT Background Intensive care unit (ICU) delirium is a multifactorial acute brain dysfunction associated with prolonged hospitalization, increased morbidity and mortality, and higher healthcare costs. Despite these substantial negative impacts of delirium, the optimal prevention and treatment strategies are unclear.
Benedikte Liebetrau   +5 more
wiley   +1 more source

Case report: VPS16 - a new cause of generalized dystonia [Esetriport: VPS16 – a generalizált dystonia új oka]

open access: yes
Introduction - Dystonia is the third most common movement disorder, which is highly diverse, both clinically and genetically. With the rise of next-generation sequencing, the number of genes associated with dystonia is increasing.
Klivényi, Péter   +5 more
core   +1 more source

Exoskeleton‐assisted physiotherapy in school and outpatient contexts for minimally ambulant children with cerebral palsy

open access: yesDevelopmental Medicine &Child Neurology, Volume 68, Issue 11, Page 1580-1592, November 2026.
Abstract Aim To assess the clinical feasibility of lower‐limb pediatric exoskeleton‐assisted (Trexo Plus) physiotherapy for minimally ambulatory children at an outpatient center and a primary school. Secondary aims were to assess associated functional and goal‐based outcomes before and after Trexo‐based physiotherapy.
Stefanie S. Bradley   +3 more
wiley   +1 more source

Acceptability of telehealth‐delivered Alberta Infant Motor Scale for Australian parents: A mixed‐methods analysis

open access: yesDevelopmental Medicine &Child Neurology, Volume 68, Issue 11, Page 1610-1620, November 2026.
A mixed methods approach was used to describe the experiences of parents whose infants received telehealth and face‐to‐face Alberta Infant Motor Scale (AIMS) assessments. Although telehealth delivery of the AIMS was reportedly acceptable to Australian parents, around half of participants preferred face‐to‐face assessment.
Kate L Rawnsley   +3 more
wiley   +1 more source

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