Results 151 to 160 of about 781,361 (246)
ABSTRACT Aminoacyl‐tRNA synthetases (ARSs) facilitate the loading of transfer RNAs with their cognate amino acids in the cytosol (ARS1), mitochondria (ARS2), or both (dual ARS). ARS deficiencies are clinically heterogeneous and can cause severe, occasionally fatal disease.
I. J. J. Muffels +21 more
wiley +1 more source
Obsessive–Compulsive Disorder: Comorbidity, Biomarkers, Circuits, and Treatment Strategies
OCD has a high comorbidity with other psychiatric conditions, among which anxiety is the most frequent one. The shared genetic biomarkers and common neural circuits underlying the co‐occurrence of OCD and anxiety pave a new path for understanding the pathogenic mechanism of OCD and suggest tailored and integrative treatment therapies for OCD from the ...
Xiao‐Yang Zhang +9 more
wiley +1 more source
Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He +4 more
wiley +1 more source
Suspected hyperthyroidism‐associated myoclonus in a cat
Abstract A 10‐year‐old, male, neutered domestic shorthair cat presented with a 2‐week history of progressively worsening myoclonic jerks predominantly involving the head. Jerks were continuous and marked at rest, but became less intense during activity.
Magdalena Maria Dyrka +5 more
wiley +1 more source
ABSTRACT Background Intensive care unit (ICU) delirium is a multifactorial acute brain dysfunction associated with prolonged hospitalization, increased morbidity and mortality, and higher healthcare costs. Despite these substantial negative impacts of delirium, the optimal prevention and treatment strategies are unclear.
Benedikte Liebetrau +5 more
wiley +1 more source
Introduction - Dystonia is the third most common movement disorder, which is highly diverse, both clinically and genetically. With the rise of next-generation sequencing, the number of genes associated with dystonia is increasing.
Klivényi, Péter +5 more
core +1 more source
Abstract Aim To assess the clinical feasibility of lower‐limb pediatric exoskeleton‐assisted (Trexo Plus) physiotherapy for minimally ambulatory children at an outpatient center and a primary school. Secondary aims were to assess associated functional and goal‐based outcomes before and after Trexo‐based physiotherapy.
Stefanie S. Bradley +3 more
wiley +1 more source
A mixed methods approach was used to describe the experiences of parents whose infants received telehealth and face‐to‐face Alberta Infant Motor Scale (AIMS) assessments. Although telehealth delivery of the AIMS was reportedly acceptable to Australian parents, around half of participants preferred face‐to‐face assessment.
Kate L Rawnsley +3 more
wiley +1 more source
The Stomatognathic System as an Expanding Frontier for Botulinum Toxin Therapy. [PDF]
Yoshida K.
europepmc +1 more source

