Results 31 to 40 of about 47,866 (259)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Leiomioma facial: Presentación de un caso

open access: yesRevista Cubana de Estomatología, 2003
Se presenta un caso de leiomioma facial. Hasta el 2002 se habían reportado aproximadamente 70 casos en la región bucal y maxilofacial. Teniendo en cuenta la escasa frecuencia de esta entidad, se consideró de interés aportar un nuevo caso, comentando los ...
Oscar García-Roco Pérez   +3 more
doaj  

Extramedullary manifestation of multiple myeloma presenting as infraorbital swelling: a rare case report

open access: yesJournal of Rare Diseases
Background Plasma cells originate from B lymphocytes and play a vital role in immune defence by producing immunoglobulins. Malignant transformation of these cells results in plasma cell neoplasms, of which multiple myeloma (MM) is the most common.
Srilatha Kavarthapu   +4 more
doaj   +1 more source

Evaluation of The Results of Preservation of Great Auricular Nerve during Parotid Surgery [PDF]

open access: yesZagazig University Medical Journal
Background: Parotid surgery serves as a standard intervention for addressing various conditions, including both benign and malignant neoplasms and inflammatory and autoimmune conditions. This study aimed to assess the effectiveness of preservation of the
Amira Ibrahim   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Juvenile psammomatoid ossifying fibroma: A radiolucent lesion to suspect preoperatively

open access: yesRadiology Case Reports, 2019
We present the cases of 2 expansive juvenile psammomatoid ossifying fibromas from sinonasal origin. Our first patient presented with a fronto-ethmoidal mass invading the orbit and the cranial base and had a bicoronal approach for tumor removal.
Sally Nguyen, MD   +4 more
doaj   +1 more source

RETRACTED: CHOICE OF OSTEOFIXATION OF EPITHESIS IN TOTAL DEFECT OF THE MAXILLOFACIAL REGION

open access: yesВестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2021
RETRACTED ARTICLERelevance. Surgical treatment of neoplasms, various genetic disorders and facial trauma often contribute to a violation of the general aesthetic perception of a person and the development of dysfunctions [1].
N. I. Tcherezova
doaj   +1 more source

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