Results 51 to 60 of about 47,866 (259)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A 3D surface coil with deep learning‐based noise reduction for parotid gland imaging at 7T

iRADIOLOGY
Background Background: Parotid gland neoplasms occur near the facial nerve. Hence, it is crucial to determine whether the malignant neoplasms involve the facial nerve and whether sacrifice of the nerve in surgery is necessary.
Sayim Gokyar, Chenyang Zhao, Shajan Gunamony, Liyang Tang, Jonathan West, Niels Kokot, Danny J. J. Wang   +6 more
doaj   +1 more source

Systematic review and meta-analysis of modified facelift incision versus modified Blair incision in parotidectomy

Scientific Reports, 2021
Surgical removal is the treatment of choice for many neoplasms of the parotid gland. This meta-analysis aimed to evaluate the differences between parotidectomy using a modified facelift incision (MFI) and parotidectomy using a modified Blair incision ...
Yi-Chan Lee, Wei-Chih Liao, Shih-Wei Yang, Cheng-Ming Luo, Yao-Te Tsai, Ming-Shao Tsai, Yi-Hsuan Lee, Li-Jen Hsin   +7 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Chondroblastoma with Secondary Aneurysmal Bone Cyst in the Sphenoid Sinus: A Case Report

대한영상의학회지, 2017
Chondroblastomas are rare benign cartilaginous neoplasms found in young patients. These tumors typically arise in the epiphysis or apophysis of a long bone. Chondroblastomas arising in the skull and facial bones are extremely rare.
Sung Hwan Cho, In Kyu Yu, Seong Min Kim, Ju Heon Kim, Seung Yeon Lee   +4 more
doaj   +1 more source

Nasal reconstruction with silicone using customised impression technique

The Journal of Indian Prosthodontic Society, 2018
Facial defects can result from a variety of reasons including trauma, burns, infections, congenital disorders, and neoplasms which require surgical correction or prosthetic rehabilitation or both.
Sanath Shetty, Fahad Mohammed, Janavi Kamath, K Kamalakanth Shenoy   +3 more
doaj   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Vascular Lesions on the Left Upper Gingiva in a Patient With Port‐Wine Stains

Clinical Case Reports
Port‐wine stain patients may develop asymptomatic intraoral capillary hemangiomas ipsilateral to facial lesions. Multidisciplinary management is critical to differentiating these from neoplasms, mitigating bleeding risks, and optimizing therapies like ...
Tinglan Yang, Mengmeng Song, Qing Liu, Zhenlai Zhu   +3 more
doaj   +1 more source