The aims of this study were to evaluate the effect of a high dose (160 mg /kg) of methylprednisolone sodium succinate ( MPSS) on the formation of endogenous nitric oxide (NO) in the brainstem after facial nerve transection and to explore whether this ...
CHEN, YUH-SHYANG;TSENG, FEN-YU;TAN, CHING-TING;LIN-SHIAU, SHOEI-YN;HSU, CHUAN-JEN +1 more
core +1 more source
Microglial responses around intrinsic CNS neurons are correlated with axonal regeneration [PDF]
Background: Microglia/macrophages and lymphocytes (T-cells) accumulate around motor and primary sensory neurons that are regenerating axons but there is little or no microglial activation or T-cell accumulation around axotomised intrinsic CNS neurons ...
Bernadette ZY Wong +20 more
core +1 more source
Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi +8 more
wiley +1 more source
ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang +23 more
wiley +1 more source
Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
Use of intraoperative monitoring of facial nerve during parotid gland tumour removal
The neuromonitor has found widespread use in parotidectomies for the purposes of avoiding or minimising insult to the facial nerve. However, its exact utility has been questionable, with differing opinions regarding its most appropriate application ...
Mukhtar, Insha Ul-Haq
core
Outcome of different facial nerve reconstruction techniques [PDF]
IntroductionThere is no technique of facial nerve reconstruction that guarantees facial function recovery up to grade III.ObjectiveTo evaluate the efficacy and safety of different facial nerve reconstruction techniques.MethodsFacial nerve reconstruction ...
Ishikawa,Kazuo +14 more
core +1 more source
Long‐Term Neurologic Exam Findings in People Diagnosed and Treated During Acute HIV Infection
ABSTRACT Objective Evaluate clinical and laboratory correlates of abnormal neurologic exam findings after acute HIV infection (AHI). Methods Participants from the RV254/SEARCH 010 cohort in Bangkok underwent standardized neurologic examinations at Weeks 0 (AHI), 12, 96, and 288 following antiretroviral therapy (ART).
Kathryn B. Holroyd +118 more
wiley +1 more source
Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu +7 more
wiley +1 more source
Morphometric Study of Hypoglossal and Facial Nerves and its Significance in Hypoglossal-Facial Nerve Anastomosis [PDF]
Background: During the repairing of facial nerve injury most common nerve used is the hypoglossal nerve. Aim and Objectives: To measure the distance between the anatomical landmarks, facial nerve and hypoglossal nerve which will be beneficial to ...
Vikram Palimar +2 more
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