Trigeminal neuralgia is a paroxysmal, intense electric shock-like, or knife-like, recurrent pain that affects one or more sense areas of the unilateral facial trigeminal nerve.
Hao Zhou +10 more
doaj +1 more source
Cranial neuralgias: from physiopathology to pharmacological treatment [PDF]
Cranial neuralgias are paroxysmal painful disorders of the head characterised by some shared features such as unilaterality of symptoms, transience and recurrence of attacks, superficial and "shock-like" quality of pain and the presence of triggering ...
BILO, LEONILDA +4 more
core +1 more source
Treatment strategy in stereotactic radiosurgery for trigeminal neuralgia, essential tremor, and coexisting intracranial tumors: The impact of biologically effective dose on clinical outcome. [PDF]
Abstract Background Gamma Knife radiosurgery (GKRS) is a well‐established treatment for trigeminal neuralgia (TN) and essential tremor (ET). In patients with coexisting intracranial tumors, radiosurgery can potentially address functional and oncologic targets in a single or staged session.
Sinha S +8 more
europepmc +2 more sources
Trigeminal neuralgia - diagnosis and treatment [PDF]
Introduction Trigeminal neuralgia (TN) is characterized by touch-evoked unilateral brief shock-like paroxysmal pain in one or more divisions of the trigeminal nerve. In addition to the paroxysmal pain, some patients also have continuous pain.
Bendtsen, Lars +3 more
core +1 more source
Combination of pharmacotherapy and lidocaine analgesic block of the peripheral trigeminal branches for trigeminal neuralgia: a pilot study [PDF]
Classical trigeminal neuralgia (CTN) is treated predominantly by pharmacotherapy but side effects and unsuccessful occurs. The current study was carried out to evaluate the therapeutic effect of combination of pharmacotherapy and lidocaine block ...
Bruti, Gianluca +9 more
core +3 more sources
Clinical insights on Tolosa Hunt syndrome: a multidisciplinary approach on neurological-related symptomatology in maxillofacial region [PDF]
Background Tolosa–Hunt syndrome (THS) related neurological symptoms are described in literature as “unilateral”, “recurrent”, “episodic”, “intense”, “severe”, “lancinating” or “stabbing” pain on the upper face and forehead and may be misdiagnosed ...
Ahmed Siddiqui, Ammar +8 more
core +2 more sources
Triggering trigeminal neuralgia [PDF]
Introduction: Although it is widely accepted that facial pain paroxysms triggered by innocuous stimuli constitute a hallmark sign of trigeminal neuralgia, very few studies to date have systematically investigated the role of the triggers involved. In the
Cruccu, Giorgio +4 more
core +1 more source
Objective: Postherpetic neuralgia (PHN) is the most common complication of herpes zoster, manifesting as a persistent, spontaneous, knife-like pain or paroxysmal burning that seriously affects a patient’s quality of life. An effective treatment of PHN is
Yuanyuan Ding +6 more
semanticscholar +1 more source
The lesion of the sensorial nerves of the face is expressed by painful phenomena called neuralgias of the brainstem or its branches. These may be idiopathic or essential and secondary or symptomatic and their clinical evidence and course are different ...
A J Brito
doaj +1 more source
Challenges recruiting to a proof-of-concept pharmaceutical trial for a rare disease: The trigeminal neuralgia experience [PDF]
Background: This study aimed to describe recruitment challenges encountered during a phase IIa study of vixotrigine, a state and use-dependent Nav1.7 channel blocker, in individuals with trigeminal neuralgia.
Bendtsen, Lars +10 more
core +4 more sources

