Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Energy coupling of facilitated transport of inorganic ions in Rhodopseudomonas sphaeroides [PDF]
, 1982 K.J. Hellingwerf +4 more
openalex +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Towards a better understanding of the political economy of regional integration in the GMS: Stakeholder coordination and consultation for subregional trade facilitation in Thailand [PDF]
This paper examines the importance, involvement, influence, impact and interest of various group of Thai stakeholders in GMS regional integration, focusing in particular on trade facilitation initiatives, i.e., the GMS Economic Corridors and the Cross ...
Kornkarun Cheewatrakoolpong
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
The Impact of Information Technology in Trade Facilitation on Small and Medium Enterprises in the Philippines [PDF]
The paper is focusing on electronic lodgment through web-based applications of value-added service providers as the IT-based trade facilitation measure, the survey of Customs Brokers conducted in this study revealed that lodgment time in the Philippines ...
Loreli C. de Dios
core
Facilitation and Grant Management Project Evaluation [PDF]
, 2008 The Facilitation and Grant Management project involves two separate aspects: the administration and organisation of RIC meetings, and development of associated projects and protocols; and the administration of grants.
Carrahar, Michelle +2 more
core
Excitation lines and the breakdown of Stokes-Einstein relations in supercooled liquids
, 2003 By applying the concept of dynamical facilitation and analyzing the excitation lines that result from this facilitation, we investigate the origin of decoupling of transport coefficients in supercooled liquids. We illustrate our approach with two classes
A. B. Bortz +14 more
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
P03.05 Supporting function of nurses to facilitate TTFields therapy for primary and recurrent Glioblastoma in clinical routine [PDF]
, 2018 Mandy Kilias +2 more
openalex +1 more source