Results 131 to 140 of about 259,377 (305)

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

The importance of understanding the multiple dimensions of power in stakeholder participation for effective biodiversity conservation

open access: yesPeople and Nature
Biodiversity conservation are increasingly focused on involving stakeholder engagement, making power a key concept in understanding its success and failure.
L. Lécuyer   +12 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Positive interactions in ecology: filling the fundamental niche

open access: yesIdeas in Ecology and Evolution, 2012
The role of negative interactions in shaping ecological communities and the realized niches of species has been a focus of considerable research for at least decades.
Mariano A. Rodriguez-Cabal   +2 more
doaj  

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Assessing the potential benefit of trade facilitation : A global perspective [PDF]

open access: yes
The relationships between trade facilitation, trade flows, and capacity building are complex and challenging to assess, both empirically and in implementation.
Wilson, John S.   +2 more
core  

Digital and sustainable trade facilitation : global report 2025

open access: yes
Based on the United Nations Global Survey on Digital and Sustainable Trade FacilitationThis report was jointly prepared by five United Nations regional commissions for Africa (ECA), Europe (ECE), Asia and the Pacific (ESCAP), Latin America and the ...
UN.ESCWA   +5 more
core   +1 more source

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