Results 141 to 150 of about 259,377 (305)
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
The Development Impact of Information Technology in Trade and Facilitation [PDF]
Trade Facilitation (TF), or streamlining regulatory and other procedures involved in the import or export of goods, has received increasing attention in recent years as governments realize the significant impact inefficient trade procedures can have on ...
Florian A. Alburo, Yann Duval
core
Mentoring in Teaching Education
ACROSSThe modern educational space positions pedagogical mentoring as an essential component of the professional development support system for educational practitioners.
Ludmila ARMASU-CANTIR +4 more
doaj
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Trade Facilitation Measures under Free Trade Agreements: Are They Discriminatory against Non-Members? [PDF]
Are trade facilitation measures under free trade agreements (FTAs) discriminatory? This important question has yet to be sufficiently explored by the existing literature on trade facilitation.
Tafgar, Aiken +2 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Digital and sustainable trade facilitation in the Organisation of Islamic Cooperation (OIC) Asian Countries [PDF]
Based on the 2023 United Nations Global Survey on Digital and Sustainable Trade Facilitation, the report analyzes the current state of trade facilitation in Organisation of Islamic Cooperation (OIC) Asian Countries, offering valuable insights into trade ...
UN.ESCAP +2 more
core +1 more source
Embedding Research in Clinical Practice: The Integrated Research Enablement Framework (IREF). [PDF]
Aust J Rural HealthFlenady T.
europepmc +1 more source