Results 151 to 160 of about 647,705 (285)

New approach to the treatment of separatrix chaos and its application to the global chaos onset between adjacent separatrices

, 2006
We have developed the {\it general method} for the description of {\it separatrix chaos}, basing on the analysis of the separatrix map dynamics. Matching it with the resonant Hamiltonian analysis, we show that, for a given amplitude of perturbation, the ...
Mannella, R., Soskin, S. M., Yevtushenko, O. M.   +2 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Bereavement Groups for Parents Who Have Lost a Child: A Qualitative Study of Parental Experiences in a Danish Context. [PDF]

Scand J Caring Sci
Beck M, Missel M, Bergenholz H, van Manen MA.   +3 more
europepmc   +1 more source

Trade Facilitation Negotiations in the WTO: Implications for Bangladesh and Other Least Developed and Developing Countries [PDF]

This paper provides an overview of how trade facilitation has been addressed in the WTO to date, and how this may affect Bangladesh’s negotiating strategy on trade facilitation in the upcoming Cancun Ministerial and beyond.
Sarah Geddes, Wenguo Cai
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Time-dependent facilitation of homologous actions. [PDF]

Exp Brain Res
Hamel R, Savoie FA, Punt D, Jenkinson N, Hinder MR.   +4 more
europepmc   +1 more source

Towards an explicit modeling of trade facilitation in CGE models: evidence from Egypt [PDF]

This paper develops a dynamic computable general equilibrium (CGE) model incorporating trade facilitation aspects. This paper’s contributions are twofold: theoretical and empirical.
Zaki, Chahir
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Synaptic Facilitation Enhances the Reliability and Precision of High-Frequency Neurotransmission. [PDF]

J Neurosci
Bernal-Correa AM, Dagostin A, von Gersdorff H, Kushmerick C.   +3 more
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source