Results 111 to 120 of about 82,917 (311)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Digital Modelling

open access: yes, 2006
This Digital Modelling Report incorporates the previous research completed for the FM\ud Exemplar Project utilising the Sydney Opera House as a case study.

core  

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Other title: Top margins: Resource guide; Other title: Bottom margins: Ohio Facilities Construction Commission

open access: yes, 2018
Cover title.; "Created: 12/7/2018..."--Document properties screen.; "Updated December 2018"--Page 4 of cover.Overview of the Commission -- Role of Commission members -- Role of Commission staff -- Commission funding -- Commission programs -- Key K-12 ...
Ohio Facilities Construction Commission.
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Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao   +6 more
wiley   +1 more source

The Effect of School Construction on Test Scores, School Enrollment, and Home Prices [PDF]

open access: yes
This paper provides new evidence on the effect of school construction projects on home prices, academic achievement, and public school enrollment. Taking advantage of the staggered implementation of a comprehensive school construction project in a poor ...
Zimmerman, Seth, Neilson, Christopher
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Physics basis for the divertor tokamak test facility

open access: yesNuclear Fusion
This paper is dealing with the physics basis used for the design of the Divertor Tokamak Test facility (DTT), under construction in Frascati (DTT 2019 DTT interim design report (2019)) Italy, and with the description of the main target plasma scenarios ...
F. Crisanti   +77 more
doaj   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers   +7 more
wiley   +1 more source

A photovoltaic training facility on the Murdoch University engineering and energy building's north east roof

open access: yes, 2012
Murdoch University’s School of Engineering and Energy is expanding its facilities to include a, total of 8.2kWp, Photovoltaic (PV) Training Facility. This facility has incorporated four types of PV modules and equipment, including mono-crystalline, poly ...
Kempin, Stuart
core  

Metric for Automated Detection and Identification of 3D CAD Elements in 3D Scanned Data [PDF]

open access: yes, 2007
Being able to efficiently compare as-built against as-planned 3D states is critical for performing efficient building and infrastructure construction, maintenance, and management.
Bosche, Frederic Nicolas, Haas, Carl
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