Results 111 to 120 of about 82,917 (311)
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
This Digital Modelling Report incorporates the previous research completed for the FM\ud Exemplar Project utilising the Sydney Opera House as a case study.
core
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Cover title.; "Created: 12/7/2018..."--Document properties screen.; "Updated December 2018"--Page 4 of cover.Overview of the Commission -- Role of Commission members -- Role of Commission staff -- Commission funding -- Commission programs -- Key K-12 ...
Ohio Facilities Construction Commission.
core
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao +6 more
wiley +1 more source
The Effect of School Construction on Test Scores, School Enrollment, and Home Prices [PDF]
This paper provides new evidence on the effect of school construction projects on home prices, academic achievement, and public school enrollment. Taking advantage of the staggered implementation of a comprehensive school construction project in a poor ...
Zimmerman, Seth, Neilson, Christopher
core
Physics basis for the divertor tokamak test facility
This paper is dealing with the physics basis used for the design of the Divertor Tokamak Test facility (DTT), under construction in Frascati (DTT 2019 DTT interim design report (2019)) Italy, and with the description of the main target plasma scenarios ...
F. Crisanti +77 more
doaj +1 more source
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers +7 more
wiley +1 more source
Murdoch University’s School of Engineering and Energy is expanding its facilities to include a, total of 8.2kWp, Photovoltaic (PV) Training Facility. This facility has incorporated four types of PV modules and equipment, including mono-crystalline, poly ...
Kempin, Stuart
core
Metric for Automated Detection and Identification of 3D CAD Elements in 3D Scanned Data [PDF]
Being able to efficiently compare as-built against as-planned 3D states is critical for performing efficient building and infrastructure construction, maintenance, and management.
Bosche, Frederic Nicolas, Haas, Carl
core

