Results 101 to 110 of about 97,962 (296)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Mr. Vesey Wilson Cattle Handling Facility Design

open access: yes, 2016
Veasay Wilson Cattle handling facility with W. W. livestock classic and chaparell components.Design was changed upon construction due in change in location, however, all components were utilized in final ...
Clarke, C. Taylor Jr.
core  

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Overview of achievements and outlook of the IFMIF/EVEDA project

open access: yesNuclear Fusion
The Engineering Validation and Engineering Design Activities for the International Fusion Materials Irradiation Facility (IFMIF/EVEDA) project have been conducted as one of the three projects (IFMIF/EVEDA, IFERC and JT60SA) within the Broader Approach ...
K. Hasegawa   +16 more
doaj   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Intelligent BIM record model for effective asset management of constructed facility

open access: yesMATEC Web of Conferences, 2018
Asset management is a continuous process that runs throughout the lifecycle of a constructed facility. The current practice of asset management is paper-based consisting of manual inspection and proves to be time consuming, tedious, and prone to human ...
Md Aslam Hossain, Ahmad Tarmizi Haron
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Power Systems Development Facility: Design, Construction, and Commissioning Status [PDF]

open access: yes, 1996
This paper will provide an introduction to the Power Systems Development Facility, a Department of Energy sponsored, engineering scale demonstration of two advanced coal-fired power technologies; and discuss current status of design, construction and ...
Vimalchand, P.   +3 more
core  

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Divertor Tokamak Test facility project: status of design and implementation

open access: yesNuclear Fusion
An overview is presented of the progress since 2021 in the construction and scientific programme preparation of the Divertor Tokamak Test (DTT) facility. Licensing for building construction has been granted at the end of 2021. Licensing for Cat.
Francesco Romanelli   +559 more
doaj   +1 more source

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