Results 131 to 140 of about 284,660 (296)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

ENVIRONMENTAL REGULATION AND IMPLICATIONS FOR COMPETITIVENESS IN INTERNATIONAL PORK TRADE [PDF]

open access: yes
Environmental concerns linked to hog production are growing in the United States, Canada, and the European Union. New regulations controlling animal manure management are being imposed to address these concerns.
Metcalfe, Mark R.
core  

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

R.61-67 standards for wastewater facility construction [PDF]

open access: yes, 2002
This regulation establishes standards, for general and technical design requirements, for use by Department in reviewing Engineering Reports, establishing Reliability Classifications and issuing State Construction Permits or other approval actions as ...
South Carolina Department of Health and Environmental Control
core  

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Infrastructure Regulation: Promises, Perils and Principles [PDF]

open access: yes
For much of the 20th century and in most countries, network utilities, such as telecommunications, electricity, natural gas, railroads, and water supply, were vertically and horizontally integrated state monopolies under ministerial control.
Kessides, Ioannis
core  

Experimental validation of a cascaded wheel slip control strategy [PDF]

open access: yes, 2010
International audienceBoth maintaining the vehicle manoeuvrability during heavy braking and maximizing the brake force can be achieved by regulating the longitudinal wheel slip around an appropriate setpoint. In this paper, a new wheel slip controller is
Pasillas-Lépine, William   +3 more
core  

The Influence of The Environment And Mother’s Behaviour Towards Toddlers’ Diarrhea in Banjarbaru, South Kalimantan

open access: yesJurnal Pembangunan dan Alam Lestari, 2016
Diarrhea is a disease that causes high fatality in toddlers all over the world. 1.5 million children die each year due to suffering from diarrhea. Diarrhea is still a major health problem in Banjarbaru, it is included in the top 10 diseaseas in every ...
Nopy Faisal   +2 more
doaj  

Neural correlates of automatic emotion regulation and their association with suicidal ideation in adolescents during the first 90-days of residential care

open access: yesTranslational Psychiatry
Background: Suicide is the second leading cause of death for adolescents in the United States. However, relatively little is known about the forms of atypical neuro-cognitive function that are correlates of suicidal ideation (SI).
Matthew Dobbertin   +12 more
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

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