Results 101 to 110 of about 10,673,421 (236)
, 2018 Bayesian, maximum likelihood, and Beast analyses related ...
John Coran (5906039) +9 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Sensitivity Analysis for Unmeasured Confounding in Meta-Analyses
, 2019 Random-effects meta-analyses of observational studies can produce biased estimates if the synthesized studies are subject to unmeasured confounding.
Tyler J. VanderWeele (6749792) +1 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
PathogensBovine pestiviruses, namely bovine viral diarrhea virus (BVDV) and HoBi-like pestiviruses (HoBiPevs), are endemic viruses in Latin America, and the disease causes significant losses in the agricultural sector.
Blanca Lisseth Guzmán Barragán +3 more
doaj +1 more source
Clinical perspective on oxidative stress in sporadic amyotrophic lateral sclerosis
, 2013 Sporadic amyotrophic lateral sclerosis (ALS) is one of the most devastating neurological diseases; most patients die within 3 to 4 years after symptom onset.
Mitsumoto H +7 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A bibliometric analysis of pharmacology and pharmacy journals : Scopus versus Web of Science [PDF]
, 2007 Our study aims at examining the suitability of Scopus for bibliometric analyses in comparison with the Web of Science (WOS). In particular we want to explore if the outcome of bibliometric analyses differs between Scopus and WOS and, if yes, in which ...
Gorraiz, Juan, Schloegl, Christian
core +1 more source
Combining Factors from Different Factor Analyses Based on Factor Congruence
, 2018 While factor analysis is one of the most often used techniques in psychometrics, comparing or combining solutions from different factor analyses can be cumbersome even though it is necessary in several situations.
Geert Verbeke +7 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source