Results 191 to 200 of about 3,317,431 (294)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Regional disparities and multidimensional determinants of hospital bed allocation in China: spatial evidence for public health policymaking. [PDF]

Front Public Health
Hu K, Yang X, Cai Y, Li C, Zhang X, Xiao D, Yu M.   +6 more
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

A JOINT LIVESTOCK-CROP MULTI-FACTOR RELATIVE PRODUCTIVITY APPROACH

An output distance function conditional on the expansion of a second output is presented. These distance functions are used to calculate distinct relative Total Factor Productivity (TFP) scores for two jointly produced products-livestock and crops for 27
Jones, Keithly G., Arnade, Carlos A.
core  

Incontinence Quiz (IQ): Translation, Cross-Cultural Adaptation, and Psychometric Validation of the French Version. [PDF]

Healthcare (Basel)
Ribeiro A, Sousa J, Neves J, Macedo C, Lumini J.   +4 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Factor and Cluster Analysis of Willingness to Pay for Organic and Non-GM Food

A large segment of consumers appear to value niche products including organic, “non-GM,†“pesticide-free,†and “no antibiotics used†more in fresh products than in processed. About ten percent of the respondents were especially interested in non-
Bernard, John C., Gifford, Katie
core  

China's City-level CO₂ emissions from power sector between 2000 and 2019. [PDF]

Sci Data
Chen B, Gao M, Liu Y, An J, Zhang Z.
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Development and validation of the student readiness and anxiety scale for AI-assisted biology teaching (SRAS-AIBT). [PDF]

Sci Rep
Kadirhanoğulları MK, Özay Köse E.
europepmc   +1 more source