Results 91 to 100 of about 25,062,635 (240)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Group Factor Analysis

IEEE Transactions on Neural Networks and Learning Systems, 2015
Factor analysis provides linear factors that describe relationships between individual variables of a data set. We extend this classical formulation into linear factors that describe relationships between groups of variables, where each group represents either a set of related variables or a data set.
Klami Arto, Kaski Samuel, Klami Arto, Kaski Samuel, Leppäaho Eemeli, Virtanen Seppo   +5 more
openaire   +9 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The influence of students’ engagement in mathematical problem solving activities

Interdisciplinary Journal of Education Research
The ability to retain and sustain students’ engagement in mathematics is crucial for fostering a lifelong interest in a subject that often turns students off. Problem-solving techniques are dynamic, particularly when integrated into teaching and learning
Olajumoke Olayemi Salami, Erica Dorethea Spangenberg   +1 more
doaj   +1 more source

A confirmatory factor analysis of two models of sensation seeking.

, 2000
The factor structures of Zuckerman's sensation seeking scale Form V (SSSV) [Zuckerman, M., Eysenck, S. & Eysenck, H. J. (1978). Sensation seeking in England and America: cross-cultural, age and sex comparisons.
Haynes, Caroline. A., Miles, Jeremy. N. V., Haynes, Caroline Anne, Clements, Keith   +3 more
core  

A factor analysis of functional independence and functional assessment measure scores among focal and diffuse brain injury patients: the importance of bi-factor models [PDF]

, 2018
Objective: To explore the factor structure of the UK Functional Independence Measure and Functional Assessment Measure (FIM+FAM) among focal and diffuse acquired brain injury patients. Design: Criterion standard.
Burgess, J., Maltby, J., Gunn, S.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A theoretical and empirical investigation of factor analytically-based matching criteria in differential item functioning [PDF]

, 1995
Modern investigative procedures to detect differential item functioning (DIF) match examinee groups on ability before comparison. The validity of DIF procedures depends, in part, on the unidimensionality of the matching criterion; however, the most ...
Johnson, Robert Lewis, NC DOCKS at The University of North Carolina at Greensboro   +1 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The impact of factor score extraction method for exploratory factor analysis on resultant factor scores and links to behaviour in a cognitive task across independent samples differing in underlying correlation structure

For factor analysis, the link between factors and factor scores (i.e. the score each person has for a factor) is not unique. Therefore, there are different methods that have been proposed for extracting factor scores.
Jacqueline Scholl
core   +1 more source