Results 191 to 200 of about 5,158,228 (296)

Finiteness of small factor analysis models

, 2010
Mathias Drton, Xiao Han
openalex   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Risk factor analysis for deep vein thrombosis in children with acute hematogenous osteomyelitis. [PDF]

BMC Musculoskelet Disord
Zhao R, Guo J, Zhang H, Song B, Feng W, Zhu D, Wen Y, Wang Q.   +7 more
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Factor Analysis-Based Quantitative Endotyping Improves Associations With CRS Cross-Sectional and Longitudinal Outcomes. [PDF]

Int Forum Allergy Rhinol
Gleason BN, Luo Z, Agarwal A, Dong S, Harmon RL, Bai J, Liao CK, Huang J, Conley DB, Welch KC, Kern RC, Smith SS, Peters AT, Stevens WS, Kato A, Muhammad LN, Tan BK.   +16 more
europepmc   +1 more source

A Path Analysis of Factors Affecting the Receptive Vocabulary Abilities of School-Aged Children with Cochlear Implants

, 2011
허민정, 부성현, Seongwoo Ahn
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Anchor Detection Strategy in Moderated Non-Linear Factor Analysis for Differential Item Functioning (DIF). [PDF]

Appl Psychol Meas
Lee S, Kim S, Choi SW.
europepmc   +1 more source

Causality relationships between coagulation factors in type 2 diabetes mellitus: path analysis approach.

, 2014
Mohammad Reza Dayer, Maysam Mard‐Soltani, Mohammad Saaid Dayer, Seyed Mohammad Alavi   +3 more
openalex   +1 more source

Expression analysis of E-cad and vascular endothelial growth factor in triple-negative breast cancer patients of different ethnic groups in western China

, 2017
Weihua Jiang, Yongtao Li, Jianghua Ou, Xiaowen Wang, Zhang Chen-guang, Lina Yi, Laiti Xue, Mingshuai Zhang   +7 more
openalex   +1 more source