Results 81 to 90 of about 12,866,402 (338)

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Evaluation of Facility Management by Multivariate Statistics – Factor Analysis

open access: yesSelected Scientific Papers: Journal of Civil Engineering, 2013
Facility management is evolving, there is no exact than other sciences, although its development is fast forward. The knowledge and practical skills in facility management is not replaced, on the contrary, they complement each other.
Singovszki Miloš, Vranayová Zuzana
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Investigation of the Sanitary Facilities of Primary Schools in Tabriz

open access: yesپژوهش‌های سلامت‌محور, 2020
Investigation of the Sanitary Facilities of Primary Schools in Tabriz     Ganjvar Azar1, Talebi Behnam2*   1. M.Sc. in Educational Sciences, Department of Educational Sciences, Faculty of Humanities and Educational Sciences, Islamic Azad University ...
Azar Ganjvar, Behnam Talebi
doaj  

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

On-the-Job E-Learning: Workers’ Attitudes and Perceptions

open access: yesInternational Review of Research in Open and Distributed Learning, 2013
The use of e-learning for on-the-job training has grown exponentially in the last decade due to it being accepted by people in charge of businesses. Few papers have explored virtual training from the workers’ standpoint, that is, the perception they have
Josep-Maria Batalla-Busquets   +1 more
doaj  

Emergência de plântulas de abóbora a partir da avaliação da qualidade das sementes Squash seedlings emergency from seed quality evaluation

open access: yesCiência Rural, 2010
O objetivo do estudo foi identificar as variáveis da análise de sementes de abóbora que melhor predizem a emergência de plântulas dessa cultura. O trabalho foi realizado no Departamento de Fitotecnia da Universidade Federal de Santa Maria.
Alexandra Augusti Boligon   +2 more
doaj   +1 more source

Association of dietary patterns and hyperuricemia: a cross-sectional study of the Yi ethnic group in China

open access: yesFood & Nutrition Research, 2018
Background: Diet plays an important role in the development of hyperuricemia (HUA), but evidence for association between overall dietary patterns and HUA is scarce and inconsistent.
Xirun Liu   +8 more
doaj   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

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