Results 181 to 190 of about 10,719,417 (281)

Identification and Characterization of SRSF2 as a Splicing-Relevant Factor Associated with the Distribution of Membranous to Secreted PD-L1, Exemplarily Considered on Human Renal Tissue, Including Renal Cell Carcinoma. [PDF]

Cancers (Basel)
Hohmann T, Hohmann U, Dehghani F, Borgmann H, Grisk O, Pryymachuk G, Jasinski-Bergner S.   +6 more
europepmc   +1 more source

RNF128 expression in lung adenocarcinoma is a favorable prognostic factor associated with decreased tumor-associated macrophages. [PDF]

Thorac Cancer, 2023
Fujimoto S, Kyuichi K, Kaede Y, Chihiro Y, Emi I, Ryo I, Reiji H, Toshiki Y, Yokomise H.   +8 more
europepmc   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

USP10 inhibits the degradation of α-synuclein, a pathogenic factor associated with Parkinson's disease, by inhibiting chaperone-mediated autophagy. [PDF]

J Biol Chem
Anisimov S, Takahashi M, Kakihana T, Katsuragi Y, Sango J, Abe T, Fujii M.   +6 more
europepmc   +1 more source

High polygenic risk score is a risk factor associated with colorectal cancer based on data from the UK Biobank. [PDF]

PLoS One, 2023
Yang M, Narasimhan VM, Zhan FB.
europepmc   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Environmental PM_2.5 Exposure: An Ignored Factor Associated with Blood Cadmium Level in Hemodialysis Patients. [PDF]

Ther Clin Risk Manag
Hsu CW, Chan MJ, Weng CH, Tsai TY, Yen TH, Huang WH.   +5 more
europepmc   +1 more source

Pectoralis muscle index might be a factor associated with frailty in older women with breast cancer. [PDF]

Turk J Med Sci, 2023
Kızılarslanoğlu MC, Eryılmaz MA, Yortanlı BÇ, Ünal İR, Ünal BC, Baran N, Altunkeser A, Aksoy N.   +7 more
europepmc   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Ornithine decarboxylase antizyme 2 (OAZ2) in human colon adenocarcinoma: a potent prognostic factor associated with immunity. [PDF]

Sci Rep
Liu Y, Zhang S, Liao W, Qian J, Lu C, Jin L.   +5 more
europepmc   +1 more source