Results 51 to 60 of about 16,335,704 (243)

Comparative frequency of Coagulation Factor II and Coagulation Factor V Alleles among new-born and senior citizens [PDF]

, 2005
Resistance to activated protein C is one of the most common inherited disorders associated with hereditary thrombophilia. A missense mutation in the gene coding for coagulation factor V (CF V Leiden) and which renders this procoagulant factor resistant ...
Bezzina Wettinger, Stephanie, Scerri, Christian A., Felice, Alex, Abela Medici, Joseph, Grochowska, Alicha   +4 more
core  

The GAGA factor regulatory network: Identification of GAGA factor associated proteins.

PLoS ONE, 2017
The Drosophila GAGA factor (GAF) has an extraordinarily diverse set of functions that include the activation and silencing of gene expression, nucleosome organization and remodeling, higher order chromosome architecture and mitosis.
Dmitry Lomaev, Anna Mikhailova, Maksim Erokhin, Alexander V Shaposhnikov, James J Moresco, Tatiana Blokhina, Daniel Wolle, Tsutomu Aoki, Vladimir Ryabykh, John R Yates, Yulii V Shidlovskii, Pavel Georgiev, Paul Schedl, Darya Chetverina   +13 more
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Performance of AAV8 vectors expressing human factor IX from a hepatic-selective promoter following intravenous injection into rats [PDF]

, 2008
Background: Vectors based on adeno-associated virus-8 (AAV8) have shown efficiency and efficacy for liver-directed gene therapy protocols following intravascular injection, particularly in relation to haemophilia gene therapy. AAV8 has also been proposed
Amit Nathwani, Baker, AH, Lorraine M Work, Tracey Graham, McIntosh, JB, Jenny McIntosh, Nathwani, A, Work, LM, Graham, T, McIntosh, J, Andrew H Baker   +10 more
core   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Hyperuricemia and associated factors among hypertensive patients attending an academic hospital of Ethiopia: A cross-sectional study

Metabolism Open
Background: Hypertension is a major public health problem in developing countries. Globally, nearly 1.13 billion adults had hypertension in 2015 and this is estimated to increase to 1.56 billion by 2025.
Oman Philmon Daka, Tesfahun Bekele Jember, Kibur Hunie Tesfa   +2 more
doaj   +1 more source

Prevalence of and factors associated with scrub typhus exposure among the hill tribe population living in high incidence areas in Thailand: a cross-sectional study

BMC Public Health, 2023
Background Scrub typhus is a significant tropical disease, occurring in rural settings and therefore usually afflicting remote agricultural populations who have lower socioeconomic status and limited access to medical care. A large proportion of the hill
Nidanuch Tasak, Tawatchai Apidechkul, Andrew C. K. Law, Mohammad Yazid Abdad, Peeradone Srichan, Carlo Perrone, Ampai Tanganuchitcharnchai, Jantana Wongsantichon, Stuart D. Blacksell   +8 more
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Assessment of impaired glomerular filtration rate and associated factors in South West Ethiopia: a cross-sectional study

BMC Nephrology
Introduction Currently, kidney disease is an increasing major health problem worldwide. It is expected to be the 5th ranked cause of death by 2040. If it is early detected, further complication caused by kidney disease will be minimized. An assessment of
Bisrat Fikadu Habtu, Gizachew Ayele, Habtamu Belay, Seid Abrar, Dereje Abebe, Nigus Chekole   +5 more
doaj   +1 more source

Factors associated with tuberculosis in cattle in the urban and peri-urban areas of Ouagadougou, Burkina Faso, 2021

Journal of Interventional Epidemiology and Public Health
Introduction: Bovine tuberculosis is endemic in Burkina Faso. It is a chronic zoonosis with a significant health and economic impact. Studies carried out on both sides of the country show the existence of bovine tuberculosis with a high prevalence ...
Djenebou Diakité, Laibané Dieudonné Dahourou, Djibril Barry, Pauline Kiswendsida Yanogo, Yoda Hermann, Jéan Kaboré, Brice Wilfrid Bicaba, Nicolas Meda, Lamouni Habibata Zerbo, Samba Thioub, Lalidia Bruno Ouoba, Sayouba Ouédraogo, Désiré Nana   +12 more
doaj   +1 more source