Results 71 to 80 of about 5,206,551 (296)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Hyperuricemia and associated factors among hypertensive patients attending an academic hospital of Ethiopia: A cross-sectional study

Metabolism Open
Background: Hypertension is a major public health problem in developing countries. Globally, nearly 1.13 billion adults had hypertension in 2015 and this is estimated to increase to 1.56 billion by 2025.
Oman Philmon Daka, Tesfahun Bekele Jember, Kibur Hunie Tesfa   +2 more
doaj   +1 more source

Prevalence of and factors associated with scrub typhus exposure among the hill tribe population living in high incidence areas in Thailand: a cross-sectional study

BMC Public Health, 2023
Background Scrub typhus is a significant tropical disease, occurring in rural settings and therefore usually afflicting remote agricultural populations who have lower socioeconomic status and limited access to medical care. A large proportion of the hill
Nidanuch Tasak, Tawatchai Apidechkul, Andrew C. K. Law, Mohammad Yazid Abdad, Peeradone Srichan, Carlo Perrone, Ampai Tanganuchitcharnchai, Jantana Wongsantichon, Stuart D. Blacksell   +8 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Activation of transforming growth factor beta by malaria parasite-derived metalloproteinases and a thrombospondin-like molecule [PDF]

, 2003
Much of the pathology of malaria is mediated by inflammatory cytokines (such as interleukin 12, interferon gamma, and tumor necrosis factor alpha), which are part of the immune response that kills the parasite.
Riley, Eleanor M, Sultan, Ali A, J. Brian de Souza, de Souza, J Brian, Eleanor M. Riley, Corran, Patrick H, Patrick H. Corran, Omer, Fakhreldin M, Riley, EM, Sultan, AA, Corran, PH, Ali A. Sultan, Omer, FM, de Souza, JB, Fakhreldin M. Omer   +14 more
core   +1 more source

Factors associated with tuberculosis in cattle in the urban and peri-urban areas of Ouagadougou, Burkina Faso, 2021

Journal of Interventional Epidemiology and Public Health
Introduction: Bovine tuberculosis is endemic in Burkina Faso. It is a chronic zoonosis with a significant health and economic impact. Studies carried out on both sides of the country show the existence of bovine tuberculosis with a high prevalence ...
Djenebou Diakité, Laibané Dieudonné Dahourou, Djibril Barry, Pauline Kiswendsida Yanogo, Yoda Hermann, Jéan Kaboré, Brice Wilfrid Bicaba, Nicolas Meda, Lamouni Habibata Zerbo, Samba Thioub, Lalidia Bruno Ouoba, Sayouba Ouédraogo, Désiré Nana   +12 more
doaj   +1 more source

Lifespan and associated factors of peripheral intravenous Cannula among infants admitted in public hospitals of Mekelle City, Tigray, Ethiopia, 2016

BMC Nursing, 2017
Background Peripheral Intravenous cannula (IV) is the most common vascular access device used to administer medications with the exception of medication or fluid with high or low PH or hyperosmolarity which may cause severe damage to small veins.
Eskedar Birhane, Kalayou Kidanu, Mekuria Kassa, Dawit Gerezgiher, Lidia Tsegay, Brhanu Weldu, Genet Kidane, Hadgu Gerensea   +7 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Assessment of household insecticide-treated bed net ownership, utilization, and associated factors in Kersa Woreda, Jimma Zone, Southwest Ethiopia

Journal of Health, Population and Nutrition
Background An estimated 40% of the world’s population lives in malaria-prone areas, there are 300–500 million malaria episodes worldwide, and at least one million malaria fatalities occur each year which makes malaria is a major public health concern [1].
Eshetu Mesfin Tadesse, Yirgalem Shibiru Baruda, Telila Mesfin Tadesse   +2 more
doaj   +1 more source

Prevalence and factors associated with Diabetes retinopathy among type 2 diabetic patients at Northwest Amhara Comprehensive Specialized Hospitals, Northwest Ethiopia 2021

BMC Ophthalmology, 2023
Introduction The worldwide prevalence of Diabetic Retinopathy was recently estimated to be 34.6%. The prevalence of diabetic retinopathy in developed nations has been thoroughly investigated, and risk factors are well understood.
Alebachew Ferede Zegeye, Yemataw Zewdu Temachu, Chilot Kassa Mekonnen   +2 more
doaj   +1 more source