Results 131 to 140 of about 4,680,194 (246)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

DNA fragmentation factor B suppresses interferon to enable cancer persister cell regrowth. [PDF]

Nat Cell Biol
Williams AF, Gervasio DAG, Turkal CE, Stuhlfire AE, Wang MX, Mauch BE, Plawat R, Nguyen AH, Paw MH, Hairani M, Lathrop CP, Harris SH, Page JL, Hangauer MJ.   +13 more
europepmc   +1 more source

Experimentally Induced Anti-Myeloperoxidase Vasculitis Is Not Attenuated in Factor B or VISTA Deficient Mice. [PDF]

Glomerular Dis, 2022
Flórez-Barrós F, Freeley SJ, Tham EL, Robson MG.   +3 more
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Beneficial effects of vascular endothelial growth factor B gene transfer in the aged heart. [PDF]

Cardiovasc Res
Manickam N, Sultan I, Panthel J, Kujundzic H, Fischer A, Schmitz K, Ruz Jurado M, Rodriguez Morales D, John D, Glaser SF, Stilz KA, Malacarne PF, Brandes RP, Braun T, Lerchenmüller C, Betge F, Abplanalp WT, Alitalo K, Dimmeler S, Wagner JUG.   +19 more
europepmc   +1 more source

Complement component factor B has thrombin-like activity. [PDF]

Biochem Biophys Res Commun, 2021
Takahashi K, Banda NK, Holers VM, Van Cott EM.   +3 more
europepmc   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Vascular Endothelial Growth Factor B Modulates Cardiac Functions via Ferroptosis Pathways in Post-Myocardial Infarction. [PDF]

Cells
Varanasi SM, Sabharwal A, Mukherjee S, Muhammad H, Kar R, Magnano C, Dorairaj A, Wang E, Dutta S, Das P, Ekker SC, Wang Y, Mukhopadhyay D, Angom RS.   +13 more
europepmc   +1 more source

Serum vascular endothelial growth factor b and metabolic syndrome incidence in the population based cohort Di@bet.es study. [PDF]

Int J Obes (Lond), 2022
Lago-Sampedro A, Lhamyani S, Valdés S, Colomo N, Maldonado-Araque C, González-Molero I, Doulatram-Gamgaram V, Delgado E, Chaves FJ, Castaño L, Calle-Pascual A, Franch-Nadal J, Rojo-Martínez G, García-Serrano S, García-Escobar E.   +14 more
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source