Results 11 to 20 of about 4,680,194 (246)
Revisiting the identification and cDNA cloning of T cell-replacing factor/interleukin-5
Frontiers in Immunology, 2014 This is a perspective based on the paper Cloning of complementary DNA encoding T cell replacing factor and identity with B cell growth factor II, by Kinashi T, Harada N, Severinson E, Tanabe T, Sideras P, Konishi M, Azuma C, Tominaga A, Bergstedt ...
Kiyoshi eTakatsu
doaj +1 more source
Vascular Endothelial Growth Factor B and Its Signaling
Frontiers in Cardiovascular Medicine, 2018 In diabetes, compromised glucose utilization leads the heart to use FA almost exclusively for ATP generation. Chronically, this adaptation unfortunately leads to the conversion of FA to potentially toxic FA metabolites. Paired with increased formation of
Nathaniel Lal +2 more
doaj +1 more source
Factor B and C4b2a Autoantibodies in C3 Glomerulopathy
Frontiers in Immunology, 2019 C3 Glomerulopathy (C3G) is a renal disease mediated primarily by dysregulation of the alternative pathway of complement. Complement is the cornerstone of innate immunity.
Jill J. Hauer +4 more
doaj +1 more source
Lipopolysaccharide and tumor necrosis factor regulate Parkin expression via nuclear factor-kappa B. [PDF]
PLoS ONE, 2011 Inflammation and oxidative stress have been implicated in the pathophysiology of Parkinson's disease (PD) and inhibition of microglial activation attenuates degeneration of dopaminergic (DA) neurons in animal models of PD.
Thi A Tran +5 more
doaj +1 more source
Nuclear Factor-Kappa B Regulation of Osteoclastogenesis and Osteoblastogenesis [PDF]
Endocrinology and Metabolism, 2023 Maintenance of skeletal integrity requires the coordinated activity of multinucleated bone-resorbing osteoclasts and bone-forming osteoblasts. Osteoclasts form resorption lacunae on bone surfaces in response to cytokines by fusion of precursor cells ...
Brendan F. Boyce +3 more
doaj +1 more source
Rap1 Is Essential for B-Cell Locomotion, Germinal Center Formation and Normal B-1a Cell Population
Frontiers in Immunology, 2021 Integrin regulation by Rap1 is indispensable for lymphocyte recirculation. In mice having B-cell-specific Rap1a/b double knockouts (DKO), the number of B cells in lymph nodes decreased to approximately 4% of that of control mice, and B cells were present
Sayaka Ishihara +10 more
doaj +1 more source
Placenta growth factor and vascular endothelial growth factor B expression in the hypoxic lung
Respiratory Research, 2011 Background Chronic alveolar hypoxia, due to residence at high altitude or chronic obstructive lung diseases, leads to pulmonary hypertension, which may be further complicated by right heart failure, increasing morbidity and mortality. In the non-diseased
McLoughlin Paul +3 more
doaj +1 more source
Viruses, 2021 Background: Interaction between host transcription factors (TFs) and the viral genome is fundamental for hepatitis B virus (HBV) gene expression regulation.
Roxanne Hui-Heng Chong +4 more
doaj +1 more source
Transcription factor NF‐κB in glomerulonephritis [PDF]
Nephrology, 2000 SUMMARY:It is becoming increasingly evident that the transcription factor, nuclear factor‐kappa B (NF‐κB) is at the heart of the inflammatory response in all tissues, including the kidney. Studies in both human glomerulonephritis and experimental disease models provide either direct or circumstantial evidence for the activation of NF‐κB.
Russell B Auwardt +2 more
openaire +1 more source
Discrete Mathematics, 1983 AbstractFor integers a and b such that 0 ⩽ a ⩽ b, a graph G is called an [a, b]-graph if a ⩽ dG(x) ⩽ b for every vertex x of G and a factor F of a graph is called an [a, b]-factor if a ⩽ dF(x) ⩽ b for every vertex x of F. We prove the following theorems. Let 0 ⩽ l ⩽ k ⩽ r, 0 ⩽ s, 0 ⩽ u and 1 ⩽ t.
Kano, Mikio, Saito, Akira
openaire +1 more source