Results 101 to 110 of about 2,000,070 (348)

Prospects for the use of prolonged concentrates of blood clotting factor IX in the treatment of hemophilia B

, 2021
V. N. Konstantinova, T. A. Andreeva, A. V. Kim   +2 more
openalex   +1 more source

Relative concentrations of haemostatic factors and cytokines in solvent/detergent-treated and fresh-frozen plasma [PDF]

, 2017
Background Indications, efficacy, and safety of plasma products are highly debated. We compared the concentrations of haemostatic proteins and cytokines in solvent/detergent-treated plasma (SDP) and fresh-frozen plasma (FFP).
Asmis, L. M., Baulig, W., Emmert, M. Y., Seifert, B., Spahn, D. R., Theusinger, O. M.   +5 more
core  

Hydrodynamic model atmospheres for WR stars: Self-consistent modeling of a WC star wind

, 2004
We present the first non-LTE atmosphere models for WR stars that incorporate a self-consistent solution of the hydrodynamic equations. The models account for iron-group line-blanketing and clumping, and compute the hydrodynamic structure of a radiatively
Abbott, Abbott, Abbott, Auer, Carbon, Castor, Crowther, Cunto, G. Gräfener, Gayley, Gräfener, Gräfener, Hamann, Hamann, Hamann, Hamann, Hamann, Hamann, Herald, Hillier, Hillier, Hillier, Hillier, Hillier, Hummer, Koesterke, Koesterke, Koesterke, Koesterke, Krticka, Kurucz, Lamers, Lamers, Langer, Leuenhagen, Leuenhagen, Lucy, Lucy, Lucy, Lépine, Lépine, Lépine, Mihalas, Mihalas, Nahar, Nahar, Nugis, Owocki, Pauldrach, Pauldrach, Pauldrach, Puls, Puls, Rogers, Schaerer, Schaerer, Schmutz, Schmutz, Seaton, Seaton, Seaton, Sellmaier, Sim, Steffen, Vink, Vink, W.-R. Hamann   +66 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Long-term outcomes of prophylaxis with a recombinant factor VIII Fc or recombinant factor IX Fc in patients with hemophilia previously treated on demand [PDF]

, 2023
María Román, Amy D. Shapiro, Margaret V. Ragni, Helena Palmborg, Linda Bystrická, Johan Szamosi, Sandra Casiano, Hérvè Chambost   +7 more
openalex   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Cleavage and inactivation of Factor IX by granulocyte elastase. [PDF]

, 1983
A Takaki, David L. Enfield, Andrew R. Thompson   +2 more
openalex   +1 more source

CPV tests with rare kaon decays

, 2010
The K_S \to pi+/- e+ e- decay mode has been investigated using the data collected in 2002 by the NA48/1 collaboration. With about 23k signal events and 59k K_L \to pi+ pi- pi0_D normalization decays, the K_S \to pi+ pi- e+ e- branching ratio was ...
Adler, Alliegro, Appel, Barberio, Batley, Batley, Batley, Bloch, Bruno, Chen, Dubnickova, DʼAmbrosio, E. Marinova, Ecker, Fanti, Friot, Gao, Lai, Ma, Park, Sehgal, Taureg   +21 more
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Scanning by DOVAM-S Detects All Unique Sequence Changes in Blinded Analyses: Evidence that the Scanning Conditions Are Generic

BioTechniques, 2000
The [detection of virtually all mutations]-SSCP (DOVAM-S) is a highly sensitive variant of single strand conformation polymorphism (SSCP). Mutations in the factor IX gene were used to find a set of five SSCP conditions that detects virtually all ...
C.H. Buzin, C.Y. Wen, V.Q. Nguyen, G. Nozari, A. Mengos, X. Li, J.S. Chen, Q. Liu, R.A. Gatti, F.K. Fujimura, S.S. Sommer   +10 more
doaj   +1 more source