Results 241 to 250 of about 123,267 (281)

Complete F9 Gene Deletion, Duplication, and Triplication Rearrangements: Implications for Factor IX Expression and Clinical Phenotypes. [PDF]

Thromb Haemost
Ma Y, Li Y, Sun J, Liang Q, Wu R, Ding Q, Dai J.   +6 more
europepmc   +1 more source

Mechanically Programmable DNA Hydrogel Microparticles for 3D Cellular Systems

Advanced Materials, EarlyView.
DNA hydrogel microparticles are designed to exhibit controllable viscoelasticity and stiffness across three orders of magnitude from 30Pa$30 \,\mathrm{Pa}$ to 6.5kPa$6.5 \,\mathrm{kPa}$. They are uptaken into fibroblast spheroids where they are actively remodeled by cellular forces depending on their mechanical properties.
Tobias Walther, Eleni Dalaka, Gotthold Fläschner, Manuel Gómez‐González, Ilia Platzman, Sadaf Pashapour, Michelle Emmert, Pere Roca‐Cusachs, Xavier Trepat, Kerstin Göpfrich   +9 more
wiley   +1 more source

Digital Microneedles for Multiplexed Transdermal Sensing via Fluorescent QR Codes

Advanced Materials, EarlyView.
Digital fluorescent microneedles encode biochemical information in skin into scannable QR codes through threshold‐activated probes that generate binary on/off signals. By transforming analog fluorescence into discrete digital patterns, this platform enables calibration‐free, multiplexed transdermal sensing of physiologically relevant biomarkers ...
Farbod Abazar, Shahrokh Vahabi, Elena Bellotti, Martina Corsi, Irene Nocera, Paola Orlandi, Guido Bocci, Giuseppe Barillaro   +7 more
wiley   +1 more source

Self‐Powered Flexible Triboelectric‐Gated Ion‐Gel Transistor for Neuromorphic Tactile Sensing and Human Activity Recognition

Advanced Materials, EarlyView.
A fully flexible ion‐gel‐gated graphene‐channel transistor driven by a triboelectric nanogenerator enables self‐powered tactile sensing and synaptic learning. Mimicking spike‐rate‐dependent plasticity, the device exhibits frequency‐selective potentiation and depression, supporting rate‐coded neuromorphic computation even under flex.
Hanseong Cho, Seoyeon Park, Youngmin Lee, Sejoon Lee   +3 more
wiley   +1 more source

Real-world usage and effectiveness of recombinant factor VIII/factor IX Fc in hemophilia A/B: final data from the 24-month, prospective, noninterventional PREVENT study in Germany. [PDF]

Res Pract Thromb Haemost
Bidlingmaier C, Heller C, Langer F, Miesbach W, Scholz U, Oldenburg J, Nüesch E, Palmborg H, Santagostino E, Tiede A.   +9 more
europepmc   +1 more source

Safety and Efficacy of Recombinant Fusion Protein Linking Coagulation Factor IX with Albumin (rIX-FP) in Previously Untreated Patients with Hemophilia B. [PDF]

TH Open
Lemons R, Wang M, Curtin J, Lepatan LM, Male C, Peyvandi F, von Depka Prondzinski M, Wang R, McKeand W, Seifert W, Oldenburg J.   +10 more
europepmc   +1 more source

Six-Year, Real-World Use of Prophylaxis with Recombinant Factor IX-Albumin Fusion Protein (rIX-FP) in Persons with Hemophilia B: A Single-Center Retrospective-Prospective Study. [PDF]

J Clin Med
Coppola A, Rivolta GF, Quintavalle G, Matichecchia A, Riccardi F, Rossi R, Benegiamo A, Ranalli P, Coluccio V, Tagliaferri A.   +9 more
europepmc   +1 more source

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Biology of factor IX

Blood Coagulation & Fibrinolysis, 1992
Within the past 20 years or so, factor IX has been at the centre of particularly intensive studies of its physiology, pathology and biochemistry as well as its molecular genetics and biology. With the complete nucleotide sequence of its human gene determined in 1985 and the molecular defects of over 600 abnormal human factor IX genes analysed to date ...
K, Kurachi, M, Furukawa, S N, Yao, S, Kurachi   +3 more
openaire   +3 more sources