ACC astrocytes are morphologically and functionally activated in DCP‐induced chronic itch. Chemogenetic activation of these astrocytes positively modulates the calcium activity of local CaMKII+ excitatory neurons and the release of D‐serine and ATP, and exerts anti‐pruritic, anxiolytic, and anti‐depressant effects.
Ze Fan +12 more
wiley +1 more source
Dual-Enzyme Co-Catalysis Strategy for Fructooligosaccharides (FOS) Biocatalytic Synthesis for Valorization of Low-Cost Byproduct Sugarcane Molasses. [PDF]
Chen GL +6 more
europepmc +1 more source
An adequacy‐for‐purpose perspective for the environmental sciences
The range of datasets, methods, and other tools available for environmental research and decision‐making is rapidly expanding. How should the quality of these tools be evaluated? When are new resources better than existing resources? We advocate an adequacy‐for‐purpose perspective, according to which the quality of environmental research tools depends ...
Wendy S Parker +3 more
wiley +1 more source
Oritavancin as consolidation or suppressive therapy in infective endocarditis and device-related infections: real-world experience with therapeutic drug monitoring. [PDF]
Giuliano S +9 more
europepmc +1 more source
Plant‐Derived Byproducts for Probiotic Encapsulation: A Composition–Microstructure–Function Review
Plant‐derived byproducts may function as matrix‐active probiotic carriers, but interpretation requires matched comparators, matrix descriptors, and stress‐specific evaluation. ABSTRACT Probiotic delivery in foods is limited by viability losses during processing, storage, and gastrointestinal (GI) transit.
Khadijat Oladayo Ganiyu, Jian Zhao
wiley +1 more source
Integrative Network-Based Transcriptomic Analysis Identifies Niclosamide as a Candidate Repositioned Drug for Breast Cancer. [PDF]
Aydin B +4 more
europepmc +1 more source
Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley +1 more source
β-Substitution and prodrug derivation leading to identification of fosmidomycin analogs with improved herbicidal activity. [PDF]
Yang Z +6 more
europepmc +1 more source
Nonthermal Concentration of Red Beetroot Juice by Reverse Osmosis and Forward Osmosis
RO and FO were used for nonthermal concentration of red beetroot juice. Single strength juice was concentrated by RO to 17 °Brix, and by FO to 50 °Brix; color and betalain were preserved by both processes. Overall, FO is a promising method for concentrating beetroot juice.
Eugenia Avellaneda, Carmen I. Moraru
wiley +1 more source
Enhancing Probiotic Performance in Food Matrices: From Strain Selection to Bioengineering. [PDF]
Silva SRJ +5 more
europepmc +1 more source

