Results 221 to 230 of about 166,342,389 (252)

Psilocybin, From Ancestral Use to Therapeutic Potential: A Multidimensional Review of Its Pharmacological Basis and Current Perspectives

Human Psychopharmacology: Clinical and Experimental, Volume 41, Issue 5, September 2026.
ABSTRACT Objective This review critically examines psilocybin, with particular emphasis on its pharmacokinetics and pharmacodynamics, including its serotonergic, neuroplastic, and anti‐inflammatory mechanisms. It integrates historical context, preclinical and clinical evidence, and evaluates emerging therapeutic potential, safety, microdosing practices,
José Norberto Vásquez‐Bonilla
wiley   +1 more source

Integrative Multi-omics and Machine Learning Reveal the Therapeutic Mechanisms of Juanyu-Xiaozhi Formula in Metabolic Dysfunction-associated Steatotic Liver Disease and Hepatic Fibrosis via the AP-1/PPARγ/SCD1 Axis. [PDF]

J Clin Transl Hepatol
Jin Z, Huang Y, Zeng C, Zhang Y, Qiu Y, Yang Y, Liu H.   +6 more
europepmc   +1 more source

COL1A1+ Epithelial Cells Orchestrate VEGFA‐VEGFR Signaling in Endometritis Revealed by Single‐Cell Analysis

Journal of Clinical Laboratory Analysis, Volume 40, Issue 18, September 2026.
Single‐cell RNA‐seq of normal and endometritis endometrium shows reduced epithelial cells and fate divergence toward ferroptosis or ribosome/antigen‐presentation programs. COL1A1+ epithelial cells act as an AP‐1–driven hub that enhances VEGFA–VEGFR signaling and remodels the vascular microenvironment.
Chengzi Tian, Zaiyi Li
wiley   +1 more source

Nut Consumption and Long-Term Risk of All-Cause Dementia: Preliminary Findings from Three Prospective Cohort Studies. [PDF]

Nutrients
Zhao M, Yan M, Fei L, Chen H, Wu M, Li Y, Huang L, Shen J, Liu G, Guasch-Ferré M, Salas-Salvadó J, Yuan C.   +11 more
europepmc   +1 more source

Drinking waters contamination by per‐ and poly‐fluoroalkyl substances of the anthropized area of Fos‐Berre, France

Journal of Environmental Quality, Volume 55, Issue 5, September/October 2026.
Abstract Per‐ and poly‐fluoroalkyl substances (PFAS) contamination and geographical distribution were studied in drinking water from the industrial harbor of Fos‐Berre, a highly industrialized area in southern France. An analytical method for 38 PFAS was developed, using large volume injection ultra‐high performance liquid chromatography‐tandem mass ...
M. Dijoux, A. Piram, S. Augy, A. Austruy, A. Souloumiac, L. De Jong, E. Gonzales‐Camoin, J. Dron, P. Chamaret, X. Moreau, S. Gori, P. Wong‐Wah‐Chung, P. Doumenq   +12 more
wiley   +1 more source

Tumor Electric Field Therapy Inhibits Epithelial-Mesenchymal Transition, Invasion, and Migration of Glioblastoma by Targeting the c-FOS/CXCL14 Axis. [PDF]

CNS Neurosci Ther
Sun C, Liu Y, Chen J, Pei J, Li C, Lan J, Wen E, Liu J, Li Z, Chen L.   +9 more
europepmc   +1 more source

Natural Product‐Derived Vesicles in Nanotherapeutics

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Natural product‐derived vesicles (NPVs) are an emerging nature‐based nanotherapeutic that can deliver bioactive metabolites into the target site and induce beneficial mechanisms. A practical, chronological bench‐to‐bedside approach throughout the entire NPV development process is expected to resolve challenges encountered in NPV studies.
Kartiko Arif Purnomo, Tsong‐Long Hwang
wiley   +1 more source

Discovery of Protein-Derived Candidate Anticancer Peptides from Toad Poison (ChanSu) Using an Integrated Proteomics and Bioinformatics-Guided Strategy. [PDF]

Toxins (Basel)
Chen J, Wang B, Xie Y, Xue F, Shi L, Jiao Y, Lin Y.   +6 more
europepmc   +1 more source

Editorial: Neurobiological basis of substance use disorders: new findings and perspectives. [PDF]

Front Neurosci
Favoretto CA, Loss CM, Vozella V, Cruz FC.   +3 more
europepmc   +1 more source

Combining Fast Orthogonal Search with Deep Learning to Improve Low-Cost IMU Signal Accuracy. [PDF]

Sensors (Basel)
Guan J, Mounier E, Iqbal U, Korenberg MJ.   +3 more
europepmc   +1 more source