FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Factor structure and psychometric properties of an adapted HIV stigma tool for measuring disability-related stigma among smallholder farmers in Western Kenya - Findings from a cross-sectional study. [PDF]
PLoS OneJeyam A +7 more
europepmc +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Cutting It Too Fine? The Factor Structure of Fine Motor Skills From Ages 5 to 10 Years. [PDF]
Child DevSuggate SP, Karle V, Stoeger H.
europepmc +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Factor structure and reliability of the Family Resilience Scale (FRAS): adaptation with Colombian families exposed to stressful events. [PDF]
Front PsycholValencia Londoño PA +3 more
europepmc +1 more source
Factor structure of the Utrecht Work Engagement Scale in a sample of Danish and Swedish haemodialysis nurses. [PDF]
BMC NursLindberg M, Knudsen K, Lindberg M.
europepmc +1 more source
Joint Factor Performance Validity?-Network and Factor Structure of Performance Validity Measures in the Clinical Evaluation of Adult ADHD. [PDF]
Behav Sci (Basel)Raasch E +4 more
europepmc +1 more source
The German 12-Item Brief Form of the Cancer Behavior Inventory (CBI-B-D-12): Factor Structure, Reliability, and Criterion Validity. [PDF]
PsychooncologyGiesler JM +4 more
europepmc +1 more source