Results 81 to 90 of about 2,173,509 (248)

PSYCHOMETRIC CHARACTERISTICS OF THE SCALE FOR TREATMENT ADHERENCE IN TYPE 2 DIABETES MELLITUS VERSION III (EATDMIII©) IN A SAMPLE OF DIABETICS PATIENTS OF COSTA RICA [PDF]

Acta Colombiana de Psicología, 2006
The Scale for Treatment Adherence in Type 2 Diabetes Mellitus version III (EATDMIII©) was tested. It was compounded by the following factors: Family Support, Organization and Community Support, Physical Exercise, Medical Control, Hygiene and SelfCare ...
Villalobos-Pérez, Alfonso, Brenes-Sáenz, Juan C., Quirós-Morales, Diego, León-Sanabria, Giovanny   +3 more
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The Internal Structure of the WISC-V in Chile: Exploratory and Confirmatory Factor Analyses of the 15 Subtests

Journal of Intelligence
The WISC-V is a widely used scale in clinical and educational settings in Chile. Given that its use guides critical decision-making for children and adolescents, it is essential to have evidence of its psychometric properties, including validity based on
Marcela Rodríguez-Cancino, Andrés Concha-Salgado   +1 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Factor structure and external correlates of posttraumatic stress disorder symptoms among African American firefighters

Psychology Research and Behavior Management, 2016
Consuelo Arbona, Weihua Fan, Nausheen Noor Department of Psychological, Health, and Learning Sciences, University of Houston, Houston, TX, USA Abstract: This study compared the relative goodness of fit of three well-established factorial models
Arbona C, Fan W, Noor N
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

CARACTERÍSTICAS PSICOMÉTRICAS DE LA ESCALA DE ADHERENCIA AL TRATAMIENTO DE LA DIABETES MELLITUS TIPO II-VERSIÓN III (EATDM-III©) EN UNA MUESTRA DE PACIENTES DIABÉTICOS DE COSTA RICA

Acta Colombiana de Psicología, 2006
Se probó la Escala de Adherencia al Tratamiento de la Diabetes Mellitus tipo IIversión III (EATDMIII©), la cual estaba compuesta por los factores Apoyo Familiar, la Organización y Apoyo Comunal, el Ejercicio Físico, el Control Médico, el Higiene y ...
ALFONSO VILLALOBOS-PÉREZ, JUAN C. BRENES-SÁENZ, DIEGO QUIRÓS-MORALES, GIOVANNY LEÓN-SANABRIA   +3 more
doaj