Refractory Epistaxis due to Severe Factor V Deficiency with Inhibitor [PDF]
Case Reports in Hematology, 2015 Factor V deficiency secondary to inhibitors is extremely rare and can be caused by a wide collection of exposures such as bovine thrombin and beta lactamase antibiotics. The management of factor V deficiency with inhibitor is a condition treated based on
Elizabeth S. John +2 more
doaj +5 more sources
Recurrent miscarriage in a woman with congenital factor V deficiency: a case report [PDF]
BMC Pregnancy and Childbirth, 2022 Background Factor V deficiency is a rare bleeding disorder that can be either congenital or acquired. Factor V deficiency mostly present with mucosal bleeding. Coagulation factor V does not increase considerably during normal gestation.
Mohammad Shirzadi +2 more
doaj +3 more sources
A Novel Phenotype of the Factor 5 Gene Mutation (Homozygote Met1736Val and Heterozygote Asp68His) Is Associated With Moderate Factor V Deficiency [PDF]
Frontiers in Medicine, 2022 BackgroundFactor V (FV) deficiency is a rare disease, with a low incidence rate in Asia. Therefore, the F5 mutation in the Taiwanese population is poorly understood.MethodsA Chinese family with FV deficiency was included, and the patient and his family ...
Yueh-Shih Chang +8 more
doaj +4 more sources
Congenital coagulation factor V deficiency with intracranial hemorrhage. [PDF]
J Clin Lab Anal, 2022 Congenital coagulation factor V (FV) deficiency is a very rare hemorrhagic disease with an incidence of approximately one in a million. The common clinical manifestations of FV deficiency include ecchymosis and mucosal bleeding.
Yang J, Mao H, Sun L.
europepmc +4 more sources
Profiling the mutational landscape of coagulation factor V deficiency [PDF]
Haematologica, 2020 Coagulation factor V (FV) is a 330 kDa procofactor of the coagulation cascade that, upon activation, contributes to the formation of the prothrombinase complex, essential for the rapid generation of thrombin.[1][1] FV deficiency (Online Mendelian ...
Elvezia Maria Paraboschi +8 more
doaj +3 more sources
A Case of Acquired Factor V Deficiency in Patient with Bleeding [PDF]
TH Open, 2020 Low frequency of rare diseases origins from missed diagnosis addressing to poor prognosis. Acquired factor V inhibitor is a very low frequent bleeding condition (prevalence: 0.09/100,000,000–0.29/1,000,000 per year).
Davide Vetri +6 more
doaj +3 more sources
Case Report: Novel Mutation of F5 With Maternal Uniparental Disomy Causes Severe Congenital Factor V Deficiency [PDF]
Frontiers in Pediatrics, 2022 We summarized two cases of congenital factor V deficiency (FVD) associated with a novel F5 mutation, and analyzed the relationship of the clinical features and genetic characteristics in congenital FVD.
Lin Cheng, Ying Li, Wenjuan Zhou, Tao Bo
doaj +2 more sources
High Mutational Heterogeneity, and New Mutations in the Human Coagulation Factor V Gene. Future Perspectives for Factor V Deficiency Using Recombinant and Advanced Therapies. [PDF]
Int J Mol Sci, 2021 Factor V is an essential clotting factor that plays a key role in the blood coagulation cascade on account of its procoagulant and anticoagulant activity. Eighty percent of circulating factor V is produced in the liver and the remaining 20% originates in
Bernal S +9 more
europepmc +2 more sources
Hemophilia A and factor V deficiency in a girl with Turner syndrome: a case report [PDF]
Journal of Medical Case Reports, 2023 Background Hemophilia is an X-linked, recessive inherited disease caused by a defect or deficiency of one of the coagulation factors (VIII or IX). It is considered a rare disease in females.
Rawan Al khudari +3 more
doaj +2 more sources
Laparoscopic hepatectomy for hepatocellular carcinoma in a patient with congenital factor V deficiency: a case report [PDF]
Surgical Case Reports, 2022 Background Factor V (FV) deficiency is an extremely rare disease, with an incidence of 1 in 1 million. The bleeding symptoms are mild, and the prognosis is good; however, the safety of surgical treatment is unclear, because there are few available ...
Takaomi Seki +12 more
doaj +2 more sources