Results 171 to 180 of about 317,965 (247)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Genetic Confirmation of Congenital Factor V Deficiency in Korean Patients. [PDF]

Ann Lab Med, 2016
Park CH, Yoo K, Lee KO, Kim SH, Sung KW, Kim HJ.   +5 more
europepmc   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Factor V deficiency in pregnancy complicated by Rh immunization and placenta previa

Acta Obstetricia et Gynecologica Scandinavica, 1997
Giuseppe Noia, Sara DeCarolis, Valerio DeStefano, Sergio Ferrazzani, Lidia DeSantis, Brigida Carducci, Marco DeSantis, Alessandro Caruso   +7 more
doaj   +1 more source

[Pedigree analysis of novel missense mutations causing hereditary coagulation factor Ⅴ deficiency]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Qin LY, Chen Y, Hou LL, Jin YH, Lu YF, Zhang K, Wang MS.   +6 more
europepmc   +1 more source

Acquired factor V deficiency following transcatheter arterial chemoembolization for hepatocellular carcinoma: a case report. [PDF]

Int Cancer Conf J, 2017
Yamane T, Imai K, Uchiba M, Umezaki N, Yamao T, Kaida T, Nakagawa S, Hashimoto D, Yamashita YI, Chikamoto A, Yoshida N, Baba H.   +11 more
europepmc   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Factor V Deficiency in Korean Patients: Clinical and Laboratory Features, Treatment, and Outcome. [PDF]

J Korean Med Sci, 2016
Park YH, Lim JH, Yi HG, Lee MH, Kim CS.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source