Results 181 to 190 of about 41,383 (293)

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia   +4 more
wiley   +1 more source

The Predictive Value of the Tumor‐Stroma Ratio for Neoadjuvant Endocrine Therapy in Hormone Receptor‐Positive Breast Cancer

open access: yesInternational Journal of Cancer, EarlyView.
Neoadjuvant endocrine therapy (NET) can help prevent metastases and improve survival in patients with hormone receptor‐positive (HR+) breast cancer. Identifying which HR+ patients will benefit from NET, however, remains challenging. Here, in a patient cohort in the Netherlands, the authors evaluated tumor‐stroma ratio (TSR) and magnetic resonance ...
Layla Andour   +8 more
wiley   +1 more source

Transcriptome‐Based Classification of Resected Pancreatic Ductal Adenocarcinoma Enhances Prognostic Modelling Accuracy of Overall Survival Following Adjuvant Treatment

open access: yesInternational Journal of Cancer, EarlyView.
Outcomes after resection of pancreatic ductal adenocarcinoma remain highly variable, and existing prognostic models lack sufficient accuracy. Here, the authors aimed to improve survival prediction by integrating transcriptome‐based subtyping into a validated clinical model and applying it to a multicenter real‐world cohort of fresh‐frozen resection ...
Marjolein F. Lansbergen   +20 more
wiley   +1 more source

Ophthalmic Vein Thrombosis Associated with Factor V Leiden and MTHFR Mutations. [PDF]

open access: yesDiagnostics (Basel), 2023
Teodoru CA   +9 more
europepmc   +1 more source

Application of geospatial analysis for mapping the distribution of severe maternal morbidities in eastern Ethiopia: The case of the Ethiopian obstetric surveillance system

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Introduction The disparity in maternal mortality and severe morbidity between high‐ and low‐income countries is well established. Previously, we highlighted within‐country disparities in Ethiopia using demographic and health survey data. This study used enhanced obstetric surveillance data to detect subnational hotspot areas and factors ...
Sisay Mulugeta Alemu   +8 more
wiley   +1 more source

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