Results 61 to 70 of about 15,400 (157)

Is retinal vein occlusion an underrecognized paraneoplastic sentinel of lymphoma? A systematic review and meta‐analysis of ocular–haematological interactions

Acta Ophthalmologica, EarlyView.
Abstract Topic This systematic review and meta‐analysis evaluated the association between retinal vein occlusion (RVO) and lymphoma across two complementary evidence components: a qualitative clinical synthesis of RVO occurring in patients with lymphoma and a quantitative synthesis of subsequent cancer outcomes in patients with RVO. For the qualitative
Kai‐Yang Chen, Hoi‐Chun Chan, Chi‐Ming Chan   +2 more
wiley   +1 more source

Leiden Mutation and the Course of Severe Acute Pancreatitis

Общая реаниматология, 2013
Objective: to evaluate the impact of Leiden mutation on the course of severe acute pancreatitis. Subjects and methods. One hundred and twelve people were examined. Group 1 comprised 50 patients diagnosed with severe acute pancreatitis without coagulation
A. V. Ershov, V. T Dolgikh, T. I. Dolgikh, S. V. Morozov, Yu. P. Orlov, A. B. Reis   +5 more
doaj   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) C.M. de Lange   +26 more
wiley   +1 more source

Fator V de Leiden na doença de Legg-Calvé-Perthes Leiden's V-factor in Legg-Calvé-Perthes disease

Acta Ortopédica Brasileira, 2009
Trobofilias hereditárias têm sido implicadas na patogênese da doenca de Legg-Calvé-Perthes. Uma investigação do fator de risco hereditário mais comum para hipercoagulabilidade - a mutação no gene do fator V (fator V de Leiden) - foi conduzida em 20 ...
Lia Lira Olivier Sanders, Manuel Bomfim Braga Júnior, César Wagner Montenegro Cima, Rosa Maria Salani Mota, Maria Inês de M. C. Pardini, Sílvia Helena Barem Rabenhorst   +5 more
doaj   +1 more source

Venous Thromboembolism in Hematologic Malignancies: Incidence, Risk Factors, and the Role of Direct Oral Anticoagulants

European Journal of Haematology, EarlyView.
ABSTRACT Thrombotic events, particularly venous thromboembolism (VTE), are a significant source of morbidity and mortality among patients with hematologic malignancies. These patients face unique challenges due to treatment‐related complications such as thrombocytopenia, coagulopathy, and heightened bleeding risk.
Mario Biglietto, Silvia Sorella, Erminia Baldacci, Massimo Breccia, Sabina Chiaretti, Marcello Capriata, Livia Donzelli, Gianna Maria D'Elia, Salvatore Giacomo Morano, Ilaria Del Giudice, Maurizio Martelli, Cristina Santoro, Antonio Chistolini   +12 more
wiley   +1 more source

Circadian rhythms of metabolite abundance in Drosophila are largely driven by time of feeding

The FEBS Journal, EarlyView.
Circadian clocks exist in the brain and peripheral tissues such as the Drosophila fat body. Single‐nuclei transcriptomics reveal that the fat body clock generates time‐of‐day differences in metabolic gene transcription, which may also be indirectly controlled by brain clocks.
Sumit Saurabh, Charlene Y. P. Guerrero, Madelyn R. Cusick, Amanda J. Samaras, Taylor M. Stephenson, Sebastian L. Kirkpatrick, Gregory J. Matthews, Daniel J. Cavanaugh   +7 more
wiley   +1 more source

Biocatalytic synthesis of S‐adenosyl‐l‐methionine analogues for allosteric activation of cystathionine‐β‐synthase

The FEBS Journal, EarlyView.
Cystathionine‐β‐synthase (CBS) helps remove harmful homocysteine and supports the production of protective sulfur‐containing molecules. Using its natural activator, S‐adenosyl‐l‐methionine, as a template, we designed and tested 15 analogues. Three activated and stabilized the enzyme, including the newly identified S‐2‐amino‐adenosyl‐l‐methionine. These
Dalibor Nakládal, Žaneta Zajacová, Rick Oerlemans, Jana Havlikova, Gabriel Zorkócy, Lukáš Kerti, Katarína Sujová, Adrian Lengyel, Zoë van der Gun, Christina Yoseif, Adrianus Cornelis van der Graaf, Guido Krenning, Ján Kyselovič, Vladimír Frecer, Matthew R. Groves, Zdenko Levarski, André Heeres, Rob H. Henning, Leo E. Deelman   +18 more
wiley   +1 more source

Performing Large‐Scale Genetic Analysis in the Bleeding Disorders Community

Haemophilia, EarlyView.
ABSTRACT Inherited bleeding disorders encompass a diverse group of conditions caused by genetic defects affecting coagulation factors, fibrinogen, von Willebrand factor, or platelet function. Despite major advances in quantitative and functional laboratory assays, a substantial diagnostic gap remains, particularly in patients with mild or atypical ...
Anna R. Blankstein, Sterre P. E. Willems, Saskia E. M. Schols, Rosanna Asselta, Gillian Lowe, Neil V. Morgan, Paula D. James   +6 more
wiley   +1 more source

Frequency of factor V Leiden (G1691A) and prothrombin (G20210A) polymorphisms in Population of Kerman Province, Iran [PDF]

Journal of Kerman University of Medical Sciences, 2017
Background & Aims:Thromboembolism is an acute cardiovascular disease that ranges from clinically unimportant to massive embolism. Both acquired and hereditary risk factors contribute to the disease.
Nasrollah Saleh-gohari, Neda Salmani-Cheharfarsakhi   +1 more
doaj  

The Paradox of Threat: Vernacular Security Governance Among Jewish and Muslim Minorities in Four European States

Journal for the Scientific Study of Religion, EarlyView.
ABSTRACT How do religious minorities proactively manage their safety amid global crises and local hostility? This article examines these dynamics, conceptualized as “vernacular security governance,” among Jewish and Muslim populations in four European states.
Tahir Abbas, May Tamimova, Irene Trebeschi, Paul Wabnitz   +3 more
wiley   +1 more source