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Congenital deficiency of factor VII
The Indian Journal of Pediatrics, 1996A case of congenital factor VII deficiency in a five-year-old child is reported. The patient, born of a non-consanguineous marriage, presented with repeated bouts of epistaxis since childhood. The prothrombin time (PT) was markedly prolonged with a normal bleeding time (BT), partial thromboplastin time with Kaolin (PTTK) and platelet count. The patient
M, Sikka +4 more
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2018
This chapter outlines the pathophysiology, clinical presentation, inheritance, and incidence of factor VII deficiency. The chapter describes the interaction with pregnancy and discusses the medical and anesthetic management of pregnant women with factor VII deficiency, including treatment of acute hemorrhage.
James P. R. Brown, Joanne Douglas
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This chapter outlines the pathophysiology, clinical presentation, inheritance, and incidence of factor VII deficiency. The chapter describes the interaction with pregnancy and discusses the medical and anesthetic management of pregnant women with factor VII deficiency, including treatment of acute hemorrhage.
James P. R. Brown, Joanne Douglas
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Factor VII Congenital Deficiency
Pathophysiology of Haemostasis and Thrombosis, 1983In congenital factor VII deficiency the clinical picture is related to the levels of factor VII coagulant activity; when factor VΠ:C levels are very low the bleeding episodes can occur frequently. The most frequent bleedings are menorrhagia and metrorrhagia in females and hemarthrosis in both sexes.
G. Mariani, M.G. Mazzucconi
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CONGENITAL DEFICIENCY OF FACTOR VII
Australasian Annals of Medicine, 1958SummaryLaboratory investigations are described in a female patient who suffers from a congenital hæmorrhagic disorder due to deficiency of Factor VII. The one‐stage prothrombin time using brain extract was greatly prolonged, but using viper venom was normal. All tests of the intrinsic blood coagulation mechanism, including the thromboplastin generation
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LIVER TRANSPLANTATION FOR FACTOR VII DEFICIENCY
Transplantation, 2001Factor VII deficiency is a serious, potentially lethal disorder of blood coagulation caused by a defect in hepatic factor VII synthesis. We report two children, sisters, both with severe, recurrent hemorrhagic complications from factor VII deficiency, successfully treated with orthotopic liver transplantation.
D, Levi +4 more
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Congenital Factor VII Deficiency
2018Coagulation factor (F) II (prothrombin) is a vitamin K-dependent coagulation factor which has an essential role in coagulation cascade. This protein is activated to thrombin by Factor X in the presence of FV and calcium. Congenital FII deficiency is an autosomal recessive bleeding disorder with an estimated incidence of 1:2,000,000 worldwide.
Mahmood Shams, Akbar Dorgalaleh
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Case report of factor VII deficiency
The American Journal of Emergency Medicine, 1993The case of a 57-year-old woman with no personal or family history of coagulopathy or blood dyscrasia who was found to be factor VII deficient by routine laboratory testing is reported. The patient was also found to have type 2 diabetes mellitus and adenocarcinoma of the uterus in the course of her hospitalization.
A J, Hirshberg +3 more
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Paracetamol poisoning unmasking factor VII deficiency
European Journal of Gastroenterology & Hepatology, 2002We report on an 18-year-old woman who took an impulsive overdose of paracetamol. The admission international normalized ratio (INR) was prolonged which resulted in her being transferred to a specialist hepatology unit. Her clinical condition and laboratory parameters did not correlate; this prompted investigation into her coagulation profile, which ...
Andrew P, Chilton +2 more
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Thromboembolism in Congenital Factor VII Deficiency
Acta Haematologica, 1984An Israeli family of Persian origin was investigated for factor VII deficiency. The proposita, derived from a consanguineous marriage, had repeated thrombophlebitis attacks, pulmonary embolism and rectal bleeding. The family studied and the proposita had low factor VII procoagulant activity and low factor VII antigen.
T, Shifter, I, Machtey, D, Creter
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Hereditary Factor VII Deficiency in Newborns
Clinical Pediatrics, 1983Chez 2 jumeaux monozygotes decedes d'hemorragie intracrânienne l'un a 3 mois, l'autre a 30 mois.
M, Bedizel, R, Albers
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