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Advanced Healthcare Materials, EarlyView.This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li +9 more
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Deficiency of factor VII (hypoproconvertinemia): case report
А. В. Дмитриев +5 more
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Hermansky-Pudlak syndrome 2 — a novel mutation with factor VII deficiency: a fluke from India
Vibha Gupta +5 more
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An overview of inherited factor VII deficiency
Transfusion and Apheresis Science, 2019Factor VII (FVII) deficiency is the most common of the Rare Inherited Coagulation Disorders. The inheritance is autosomal recessive but there is variable penetrance. Overall there is poor correlation between the FVII level and the bleeding phenotype. Heterozygotes may have significant bleeding and severe homozygotes, or compound heterozygotes can be ...
K. Robinson
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Factor VII deficiency in China: Phenotype, genotype and current status of management
British Journal of Haematology, 2022Congenital factor VII (FVII) deficiency is a rare bleeding disorder characterised by a wide molecular and clinical heterogeneity. We investigated the clinical phenotype of 193 patients and F7 genotype of 55/193 patients with FVII deficiency throughout ...
Cuiyun Qu +5 more
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Management of pregnancy in women with factor VII deficiency: A case series
Haemophilia, 2020Inherited factor VII deficiency is the most common autosomal recessive inherited bleeding disorder, with an estimated incidence of one per 500 000 cases in the general population.
Eun-Ju Lee +3 more
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American Journal of Hematology, 1981
AbstractThis report describes three patients with factor (F) VII deficiency: two adult siblings and an unrelated 5½‐month‐old child who succumbed after several central nervous system (CNS) hemorrhages. This event prompted a review of the literature concerning the incidence and characteristics of intracranial hemorrhage in congenital F VII deficiency.Of
Ute Hasiba +3 more
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AbstractThis report describes three patients with factor (F) VII deficiency: two adult siblings and an unrelated 5½‐month‐old child who succumbed after several central nervous system (CNS) hemorrhages. This event prompted a review of the literature concerning the incidence and characteristics of intracranial hemorrhage in congenital F VII deficiency.Of
Ute Hasiba +3 more
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Factor VII Deficiency in Patients Receiving Chronic Packed Cell Transfusions.
Journal of pediatric hematology/oncology, 2020Acquired factor VII deficiency is a rare coagulopathy that has not been reported in transfusion-dependent patients so far. In this study, we reviewed files of 26 transfusion-dependent patients for coagulation profiles, factor V levels, factor VII levels,
Abed Abu-Quider +6 more
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Congenital factor VII deficiency
The Journal of Pediatrics, 1971Summary A case of factor VII deficiency in a PuertoRican boy is described. He presented with epistaxis as the only symptom. The importance of early diagnosis of the defect is stressed. Identification of heterozygous carriers is also of importance because these persons, for unknown reasons, might present with hemorrhagic diathesis.
Maria L. Falter, Mary F. Kaufman
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